1uyq: Difference between revisions

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[[Image:1uyq.png|left|200px]]


{{STRUCTURE_1uyq|  PDB=1uyq  |  SCENE= }}
==mutated b-glucosidase A from Paenibacillus polymyxa showing increased stability==
 
<StructureSection load='1uyq' size='340' side='right'caption='[[1uyq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===MUTATED B-GLUCOSIDASE A FROM PAENIBACILLUS POLYMYXA SHOWING INCREASED STABILITY===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1uyq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Paenibacillus_polymyxa Paenibacillus polymyxa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UYQ FirstGlance]. <br>
{{ABSTRACT_PUBMED_9466926}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2F:2-DEOXY-2-FLUORO-ALPHA-D-GLUCOPYRANOSE'>G2F</scene>, <scene name='pdbligand=NFG:2,4-DINITROPHENYL+2-DEOXY-2-FLUORO-BETA-D-GLUCOPYRANOSIDE'>NFG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uyq OCA], [https://pdbe.org/1uyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uyq RCSB], [https://www.ebi.ac.uk/pdbsum/1uyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uyq ProSAT]</span></td></tr>
[[1uyq]] is a 1 chain structure of [[Beta-glucosidase]] with sequence from [http://en.wikipedia.org/wiki/Paenibacillus_polymyxa Paenibacillus polymyxa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UYQ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/BGLA_PAEPO BGLA_PAEPO] BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/1uyq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uyq ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Beta-glucosidase|Beta-glucosidase]]
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:009466926</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Beta-glucosidase]]
[[Category: Paenibacillus polymyxa]]
[[Category: Paenibacillus polymyxa]]
[[Category: Isorna, P.]]
[[Category: Isorna P]]
[[Category: Polaina, J.]]
[[Category: Polaina J]]
[[Category: Sanz-Aparicio, J.]]
[[Category: Sanz-Aparicio J]]
[[Category: B-glucosidase]]
[[Category: Cellulose degradation]]
[[Category: Hydrolase]]
[[Category: Hydrolase glycosidase]]
[[Category: Mutation affecting stability]]

Latest revision as of 10:28, 9 October 2024

mutated b-glucosidase A from Paenibacillus polymyxa showing increased stabilitymutated b-glucosidase A from Paenibacillus polymyxa showing increased stability

Structural highlights

1uyq is a 1 chain structure with sequence from Paenibacillus polymyxa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

BGLA_PAEPO BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1uyq, resolution 2.20Å

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