1s96: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
← Older edit
No edit summary
No edit summary
 
(14 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1s96.gif|left|200px]]<br /><applet load="1s96" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1s96, resolution 2.0&Aring;" />
'''The 2.0 A X-ray structure of Guanylate Kinase from E.coli'''<br />


==About this Structure==
==The 2.0 A X-ray structure of Guanylate Kinase from E.coli==
1S96 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=UNX:'>UNX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA].  
<StructureSection load='1s96' size='340' side='right'caption='[[1s96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1s96]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S96 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s96 OCA], [https://pdbe.org/1s96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s96 RCSB], [https://www.ebi.ac.uk/pdbsum/1s96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s96 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KGUA_ECOLI KGUA_ECOLI] Essential for recycling GMP and indirectly, cGMP.<ref>PMID:8390989</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s9/1s96_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s96 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Guanylate kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Klock HE]]
[[Category: Klock, H E.]]
[[Category: Kreusch A]]
[[Category: Kreusch, A.]]
[[Category: Lesley SA]]
[[Category: Lesley, S A.]]
[[Category: McMullan D]]
[[Category: McMullan, D.]]
[[Category: Rodrigues K]]
[[Category: Rodrigues, K.]]
[[Category: Spraggon G]]
[[Category: Spraggon, G.]]
[[Category: Vincent J]]
[[Category: Vincent, J.]]
[[Category: PO4]]
[[Category: UNX]]
[[Category: dimer]]
[[Category: e coli]]
[[Category: guanylate kinase]]
[[Category: sad]]
[[Category: x-ray structure]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:59:07 2008''

Latest revision as of 10:26, 9 October 2024

The 2.0 A X-ray structure of Guanylate Kinase from E.coliThe 2.0 A X-ray structure of Guanylate Kinase from E.coli

Structural highlights

1s96 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KGUA_ECOLI Essential for recycling GMP and indirectly, cGMP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Gentry D, Bengra C, Ikehara K, Cashel M. Guanylate kinase of Escherichia coli K-12. J Biol Chem. 1993 Jul 5;268(19):14316-21. PMID:8390989

1s96, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1s96&oldid=4185093"