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==CRYSTAL STRUCTURE (TRIGONAL) OF BEE VENOM HYALURONIDASE==
==CRYSTAL STRUCTURE (TRIGONAL) OF BEE VENOM HYALURONIDASE==
<StructureSection load='1fcu' size='340' side='right' caption='[[1fcu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1fcu' size='340' side='right'caption='[[1fcu]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1fcu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Apime Apime]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FCU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FCU FirstGlance]. <br>
<table><tr><td colspan='2'>[[1fcu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FCU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FCU FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fcq|1fcq]], [[1fcv|1fcv]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.35 3.2.1.35] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fcu OCA], [https://pdbe.org/1fcu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fcu RCSB], [https://www.ebi.ac.uk/pdbsum/1fcu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fcu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fcu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fcu OCA], [http://pdbe.org/1fcu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fcu RCSB], [http://www.ebi.ac.uk/pdbsum/1fcu PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HUGA_APIME HUGA_APIME]] Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides (By similarity).  
[https://www.uniprot.org/uniprot/HUGA_APIME HUGA_APIME] Hydrolyzes high molecular weight hyaluronic acid to produce small oligosaccharides (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/1fcu_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/1fcu_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fcu ConSurf].
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<div style="clear:both"></div>
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==See Also==
==See Also==
*[[Hyaluronidase|Hyaluronidase]]
*[[Hyaluronidase 3D structures|Hyaluronidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Apime]]
[[Category: Apis mellifera]]
[[Category: Hydrolase]]
[[Category: Large Structures]]
[[Category: Markovic-Housley, Z]]
[[Category: Markovic-Housley Z]]
[[Category: Miglierini, G]]
[[Category: Miglierini G]]
[[Category: Mueller, U]]
[[Category: Mueller U]]
[[Category: Rizkallah, P J]]
[[Category: Rizkallah PJ]]
[[Category: Schirmer, T]]
[[Category: Schirmer T]]
[[Category: Soldatova, L]]
[[Category: Soldatova L]]
[[Category: Allergen]]
[[Category: Glycosidase family 56]]

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