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Angiotensin-Converting Enzyme 3D structures: Difference between revisions

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New page: *Angiotensin Converting Enzyme **1o8a – hANCE - human<br /> **2iul, 2iux, 3nxq, 4c2n, 4c2o, 4c2q, 4c2r – hANCE (mutant) <br /> **2c6f – hANCE N d...
 
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*Angiotensin Converting Enzyme
==3D Structures of [[Angiotensin-Converting Enzyme]]==


**[[1o8a]] – hANCE - human<br />
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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*Angiotensin Converting Enzyme N domain or RBD (1-641)
 
**[[1o8a]], [[2c6f]] – hANCE - human<br />
**[[8hrn]], [[8hru]], [[8jwh]] – hANCE 2 - Cryo EM<br />
**[[2iul]], [[2iux]], [[3nxq]], [[4c2n]], [[4c2o]], [[4c2q]], [[4c2r]] – hANCE (mutant) <br />
**[[2iul]], [[2iux]], [[3nxq]], [[4c2n]], [[4c2o]], [[4c2q]], [[4c2r]] – hANCE (mutant) <br />
**[[2c6f]] – hANCE N domain<br />
**[[7wa3]] – miANCE - mink<br />
**[[7c8k]] – baANCE – bat - Cryo EM<br />
**[[2x8y]] – DmANCE – Drosophila melanogaster<br />
**[[2x8y]] – DmANCE – Drosophila melanogaster<br />
**[[6s1y]] – moANCE N domain - mosquito<br />


*Angiotensin Converting Enzyme N domain (1-641) complex
*Angiotensin Converting Enzyme RBD (1-641) complex


**[[2c6n]], [[1o86]], [[4c2p]], [[2ydm]], [[1uze]], [[1uzf]], [[6h5x]] - hANCE + anti-hypertensive drug<br />  
**[[6zpq]], [[6zpt]] - hANCE 1 (mutant) <br />
**[[6en5]], [[6en6]], [[4bzr]] - hANCE + inhibitor<br />
**[[2c6n]], [[1o86]], [[4c2p]], [[2ydm]], [[1uze]], [[1uzf]], [[6h5x]] - hANCE 1 + drug<br />
**[[4bzs]] – hANCE (mutant) + inhibitor<br />
**[[7z6z]] - hANCE 1 (mutant) + drug<br />
**[[6f9r]], [[6f9t]], [[6f9u]], [[6f9v]] - hANCE + chronic heart failure drug<br />
**[[6en5]], [[6en6]], [[4bzr]], [[6tt4]] - hANCE 1 + inhibitor<br />
**[[3kbh]], [[3d0g]], [[3d0h]], [[3d0i]], [[2ajf]], [[3sci]], [[3scj]], [[3sck]], [[3scl]], [[6cs2]], [[6acg]], [[6acj]], [[6ack]] – hANCE 2 +spike glycoprotein<br />
**[[7q24]], [[7q25]], [[7q26]], [[7q27]], [[7q29]]  - hANCE 1 + inhibitor<br />
 
**[[4bzs]], [[6tt3]] – hANCE 1 mutant) + inhibitor<br />
**[[4bxk]], [[4ca5]], [[4ca7]], [[4ca8]], [[2xy9, [[2xyd – hANCE + phosphinic inhibitor<br />
**[[6f9r]], [[6f9t]], [[6f9u]], [[6f9v]] - hANCE 1 + chronic heart failure drug<br />
**[[4ca6]] - hANCE N domain (mutant) + phosphinic inhibitor<br />
**[[4bxk]], [[4ca5]], [[4ca7]], [[4ca8]], [[2xy9]], [[2xyd]] – hANCE 1 + phosphinic inhibitor<br />
**[[4aph]] – hANCE + angiotensin II<br />
**[[4ca6]], [[6tt1]] - hANCE 1 (mutant) + phosphinic inhibitor<br />
**[[4apj]] – hANCE + bradykinin-potentiating peptide B<br />
**[[4aph]] – hANCE 1 + angiotensin II<br />
**[[1r42]], [[1r4l]] – hANCE + disordered segment of collectrin homology domain<br />
**[[4apj]], [[6qs1]] – hANCE 1 + bradykinin-potentiating peptide B<br />
**[[8qfx]], [[8qhl]] – hANCE 1 + peptide<br />
**[[8b9p]], [[8bfw]], [[8bn1]], [[8byj]], [[8t0q]], [[8tos]], [[8tou]] – hANCE 2 + peptide<br />
**[[7e7e]] - hANCE 2 + antibody<br />
**[[8e7m]] - hANCE 2 + antibody – Cryo EM<br />
**[[1r42]], [[1r4l]] – hANCE 2 + disordered segment of collectrin homology domain<br />
**[[2xhm]] – DmANCE+K inhibitor<br />
**[[2xhm]] – DmANCE+K inhibitor<br />
**[[2x8z]], [[2x90]], [[2x91]], [[2x92]], [[2x93]], [[2x94]], [[2x95]], [[2x96]], [[2x97]], [[1j36]], [[1j37]], [[1j38]], [[3zqz]] – DmANCE+anti-hypertensive drug<br />
**[[2x8z]], [[2x90]], [[2x91]], [[2x92]], [[2x93]], [[2x94]], [[2x95]], [[2x96]], [[2x97]], [[1j36]], [[1j37]], [[1j38]], [[3zqz]] – DmANCE+anti-hypertensive drug<br />
**[[4aa1]] – DmANCE + angiotensin II<br />
**[[4aa1]] – DmANCE 1 + angiotensin II<br />
**[[4aa2]], [[4asr]] – DmANCE + bradykinin-potentiating peptide B<br />
**[[4aa2]], [[4asr]] – DmANCE 1 + bradykinin-potentiating peptide B<br />
**[[4asq]] – DmANCE + bradykinin peptide<br />
**[[4asq]] – DmANCE 1 + bradykinin peptide<br />
**[[6s1z]] – moANCE 2 + drug<br />
 
*Angiotensin Converting Enzyme N domain or RBD (1-641) complex with spike glycoprotein
 
**[[3kbh]], [[3d0g]], [[3d0h]], [[3d0i]], [[2ajf]], [[3sci]], [[3scj]], [[3sck]], [[3scl]], [[6cs2]], [[6acg]], [[6acj]], [[6ack]], [[6lzg]], [[6m0j]], [[6vw1]], [[7drv]], [[7ekc]], [[7eke]], [[7ekf]], [[7ekg]], [[7ekh]], [[7lo4]], [[7p19]], [[7p8i]], [[7sn0]], [[7u0n]], [[7ufk]], [[7vib]], [[7wbq]], [[7whh]], [[7wnm]], [[7xaz]], [[7xbf]], [[7xbh]], [[7xwa]], [[8asy]], [[8if2]], [[8sph]], [[8wds]] – hANCE 2 +spike glycoprotein<br />
**[[7dmu]], [[7efp]], [[7efr]], [[7nxc]], [[7rpv]] – hANCE 2 (mutant) + SARS-Cov-2 spike glycoprotein <br />
**[[7a91]], [[7a92]], [[7a94]], [[7a95]], [[7a96]], [[7a97]], [[7a98]], [[7bh9]], [[7ct5]], [[7ddo]], [[7ddp]], [[7df4]], [[7dqa]], [[7dx5]], [[7dx6]], [[7dx7]], [[7dx8]], [[7dx9]], [[7edj]], [[7fdg]], [[7fdh]], [[7fdi]], [[7fem]], [[7kj2]], [[7kj3]], [[7kj4]], [[7kmb]], [[7kms]], [[7kmz]], [[7knb]], [[7kne]], [[7knh]], [[7kni]], [[7l7f]], [[7mjm]], [[7mjn]], [[7p8j]], [[7r0z]], [[7r10]], [[7r11]], [[7r12]], [[7r1a]], [[7sxx]], [[7sxy]], [[7sxz]], [[7sy1]], [[7sy2]], [[7sy3]], [[7sy4]], [[7sy5]], [[7sy6]], [[7sy7]], [[7sy8]], [[7t9k]], [[7t9l]], [[7tew]], [[7tex]], [[7tez]], [[7te0]], [[7tf0]], [[7v7z]], [[7v80]], [[7v81]], [[7v82]], [[7v83]], [[7v84]], [[7v85]], [[7v86]], [[7v88]], [[7v89]], [[7v8a]], [[7v8b]], [[7vx4]], [[7vx5]], [[7vx9]], [[7vxa]], [[7vxb]], [[7vxc]], [[7vxd]], [[7vxf]], [[7vxk]], [[7vxm]], [[7w8s]], [[7w98]], [[7w99]], [[7w9b]], [[7w9c]], [[7w9i]], [[7wa1]], [[7wbl]], [[7wgb]], [[7wgc]], [[7wk4]], [[7wk5]], [[7wk6]], [[7wpa]], [[7wpb]], [[7wpc]], [[7wri]], [[7ws8]], [[7ws9]], [[7wsa]], [[7wvp]], [[7wvq]], [[7xb0]], [[7xb1]], [[7xch]], [[7xci]], [[7xid]], [[7xo7]], [[7xo8]], [[7xo9]], [[7y1y]], [[7y1z]], [[7y20]], [[7y21]], [[7y9z]], [[7ya0]], [[7ya1]], [[7yhw]], [[7yj3]], [[7yr2]], [[7yr4]], [[7zdq]], [[7zf7]], [[8aqs]], [[8dlj]], [[8dlk]], [[8dlm]], [[8dln]], [[8dlp]], [[8dlq]], [[8dlu]], [[8dlv]], [[8dm5]], [[8dm6]], [[8dv1]], [[8dv2]], [[8h06]], [[8hrl]], [[8i9b]], [[8i9c]], [[8i9e]], [[8i9f]], [[8i9g]], [[8iov]], [[8jje]], [[8jyn]], [[8jyo]], [[8jyp]], [[8vko]], [[8vkp]], [[8wdr]], [[8wdy]], [[8wdz]], [[8we0]], [[8we1]], [[8wgv]], [[8wgw]], [[8whs]], [[8whu]], [[8whz]], [[8wlz]], [[8wp8]], [[8wrh]], [[8wrl]], [[8wrm]], [[8wro]], [[8wtj]], [[8xlm]], [[8xln]], [[8xn2]], [[8xn3]], [[8xnf]], [[8xnk]], [[8y16]], [[8y18]], [[8zbq]] – hANCE 2 + SARS-Cov-2 spike glycoprotein – Cryo EM<br />
**[[7l0n]], [[7tn0]] – hANCE 2 + SARS-Cov-2 spike glycoprotein + antibody<br />
**[[7dx4]], [[7xcp]], [[7ydi]], [[7yeg]], [[8df5]], [[8fxb]], [[8fxc]], [[8s9g]], [[8we4]], [[8xsf]], [[8xsj]], [[8y6a]] – hANCE 2 + SARS-Cov-2 spike glycoprotein + antibody - Cryo EM<br />
**[[7fc5]], [[7fc6]], [[7w6r]], [[7xby]] – ANCE + SARS-Cov-2 spike glycoprotein – horse<br />
**[[8wlo]], [[8wlr]] – ANCE + SARS-Cov-2 spike glycoprotein – hippo - Cryo EM<br />
**[[8hfx]], [[8hfy]], [[8hfz]], [[8hg0]], [[8ify]], [[8ifz]] – ANCE + SARS-Cov-2 spike glycoprotein – deer - Cryo EM<br />
**[[7wsk]] – ANCE + SARS-Cov-2 spike glycoprotein – civet<br />
**[[7c8d]] – cANCE + SARS-Cov-2 spike glycoprotein – cat - Cryo EM<br />
**[[8xyz]], [[8xzb]], [[8xzd]] – ANCE + SARS-Cov-2 spike glycoprotein – fox - Cryo EM<br />
**[[7e3j]] – ANCE + SARS-Cov-2 spike glycoprotein – dog<br />
**[[8t20]], [[8t22]], [[8t23]], [[8t25]], [[8taz]] – miANCE + SARS-Cov-2 spike glycoprotein - Cryo EM<br />
**[[8wox]], [[8woy]], [[8woz]] – ANCE + SARS-Cov-2 spike glycoprotein – rabbit - Cryo EM<br />
**[[7wsg]], [[7wsh]] – ANCE + SARS-Cov-2 spike glycoprotein – seal - Cryo EM<br />
**[[7fdk]], [[7wrh]], [[7xo4]], [[7xo5]], [[7xo6]], [[7xoa]], [[7xob]], [[7xoc]], [[7yvu]], [[8aqt]], [[8aqu]], [[8aqv]], [[8aqw]], [[8dm7]], [[[8dm8]], [[8dma]], [[8vkl]], [[8vkm]], [[8vkn]] – mANCE + SARS-Cov-2 spike glycoprotein – mouse – Cryo EM<br />
**[[7ufl]], [[8uzf]] – mANCE + SARS-Cov-2 spike glycoprotein <br />
**[[8gry]] – ANCE + SARS-Cov-2 spike glycoprotein – rat – Cryo EM<br />
**[[7yv8]], [[8ka8]], [[8kc2]] – ANCE + SARS-Cov-2 spike glycoprotein – hamster – Cryo EM<br />
**[[7wse]], [[7wsf]] – ANCE + SARS-Cov-2 spike glycoprotein – whale – Cryo EM<br />
**[[7c8j]], [[7pki]] – baANCE + SARS-Cov-2 spike glycoprotein<br />
**[[7wpo]], [[7wpz]], [[8hxk]], [[8u0t]] – baANCE + SARS-Cov-2 spike glycoprotein – Cryo EM<br />
 
*Angiotensin Converting Enzyme C domain (642-1232)
 
**[[6zpu]] – hANCE 1 (mutant)<br />
**[[3l3n]] – hANCE 1 (mutant) +LISW<br />
**[[3bkk]], [[3bkl]] – hANCE 1 +ketone inhibitor<br />
**[[2oc2]] – hANCE 1 +phosphinic inhibitor<br />
**[[7q28]] – hANCE 1 (mutant) + inhibitor<br />
**[[6h5w]], [[7z70]] - hANCE 1 (mutant) + anti-hypertensive drug<br />
 
*Angiotensin Converting Enzyme residues 30-1240
 
**[[7q4c]] – hANCE 1 30-1240 – Cryo EM<br />
**[[7q3y]], [[7q49]], [[7q4d]], [[7q4e]] – hANCE 1 (mutant) 30-1240 – Cryo EM<br />
 
*Angiotensin Converting Enzyme residues 2-805 complex


*Angiotensin Converting Enzyme C domain (642-1232) complex
**[[6m1d]], [[8p2w]], [[8p2x]], [[8p2y]] – hANCE 2 + Na-dependent neutral amino acid transporter – Cryo EM<br />
**[[8i92]], [[8i93]] – hANCE 2 + Na-dependent neutral amino acid transporter + amino acid – Cryo EM<br />
**[[6m17]], [[6m18]], [[7dwx]], [[7y75]], [[7y76]] – hANCE 2 + Na-dependent neutral amino acid transporter + spike glycoprotein – Cryo EM<br />
**[[7v61]] – hANCE 2 + Na-dependent neutral aminoacid transporter + antibody – Cryo EM<br />
**[[8wby]], [[8wbz]] – hANCE 2 + Na-dependent neutral aminoacid transporter + inhibitor – Cryo EM<br />
**[[8p2z]] – hANCE 2 + Na-dependent neutral aminoacid transporter + pipecolate – Cryo EM<br />
**[[8wm3]] – hANCE 2 + Na-dependent neutral aminoacid transporter + drug – Cryo EM<br />
**[[8i91]] – hANCE 2 + Pro transporter + Pro – Cryo EM<br />
**[[8p30]], [[8p31]] – hANCE 2 + Pro transporter + pipecolate – Cryo EM<


**[[3l3n]] – hANCE+LISW<br />
**[[3bkk]], [[3bkl]] – hANCE+ketone inhibitor<br />
**[[2oc2]], [[4ca5]], [[4ca7]], [[4ca8]] - hANCE+phosphinic inhibitor<br />
**[[6h5w]] - hANCE (mutant) + anti-hypertensive drug<br />
}}
}}
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Michal Harel
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