8qjf: Difference between revisions
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The entry | ==Connexin-32 gap junction channel in complex with 2-aminoethoxydiphenyl borate== | ||
<StructureSection load='8qjf' size='340' side='right'caption='[[8qjf]], [[Resolution|resolution]] 2.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8qjf]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QJF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.86Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qjf OCA], [https://pdbe.org/8qjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qjf RCSB], [https://www.ebi.ac.uk/pdbsum/8qjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qjf ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/CXB1_HUMAN CXB1_HUMAN] X-linked Charcot-Marie-Tooth disease type 1;X-linked progressive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry. The gene represented in this entry may act as a disease modifier. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CXB1_HUMAN CXB1_HUMAN] One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Han Y]] | |||
[[Category: Korkhov VM]] | |||
[[Category: Lavriha P]] | |||
Latest revision as of 08:07, 25 September 2024
Connexin-32 gap junction channel in complex with 2-aminoethoxydiphenyl borateConnexin-32 gap junction channel in complex with 2-aminoethoxydiphenyl borate
Structural highlights
DiseaseCXB1_HUMAN X-linked Charcot-Marie-Tooth disease type 1;X-linked progressive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry. The gene represented in this entry may act as a disease modifier. FunctionCXB1_HUMAN One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
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