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Alpha-glucosidase 3D structures: Difference between revisions

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*α glucosidase
*α glucosidase


**[[3w38]] – bAGS - beet<br />
**[[8slv]] – AGS - mosquito<br />
**[[2lvx]] – fyAGS 2 MRH domain – fission yeast - NMR<br />
**[[2n1h]] – fyAGS 2 MRH domain (mutant) - NMR<br />
**[[2g3m]] – SsAGS – ''Sulfolobus solfataricus''<br />
**[[2g3m]] – SsAGS – ''Sulfolobus solfataricus''<br />
**[[2ze0]], [[5zcb]] – GeAGS – ''Geobacillus''<br />
**[[2ze0]], [[5zcb]] – GeAGS – ''Geobacillus''<br />
**[[3w38]] – bAGS - beet<br />
**[[2d73]], [[2jka]], [[3wfa]], [[5djw]], [[5f7c]], [[3wfa]], [[3a24]], [[5xfm]] – BtAGS – ''Bacterioides thetaiotaomicron''<br />
**[[2d73]], [[2jka]], [[3wfa]], [[5djw]], [[5f7c]], [[3wfa]], [[3a24]], [[5xfm]] – BtAGS – ''Bacterioides thetaiotaomicron''<br />
**[[5hq4]] – PaAGS - ''Pseudoalteromonas''<br />
**[[5hq4]] – PaAGS - ''Pseudoalteromonas''<br />
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**[[7voh]] – AGS – ''Qipengyuania seohaensis''<br />
**[[7voh]] – AGS – ''Qipengyuania seohaensis''<br />
**[[1ayx]], [[2fba]] – SfAGS – ''Saccharomycopsis fibuligera''<br />
**[[1ayx]], [[2fba]] – SfAGS – ''Saccharomycopsis fibuligera''<br />
**[[5f0e]] – mAGS - mouse<br />
**[[5aed]], [[5aee]], [[5aeg]] – AGS - ''Esherichia coli''<br />
**[[5aed]], [[5aee]], [[5aeg]] – AGS - ''Esherichia coli''<br />
**[[3wy1]] – HaAGS - ''Halomonas''<br />
**[[3wy1]] – HaAGS - ''Halomonas''<br />
**[[4xpo]] – PsAGS - ''Pedobacter saltans''<br />
**[[4xpo]] – PsAGS - ''Pedobacter saltans''<br />
**[[4xpr]] – PsAGS (mutant)<br />
**[[4xpr]] – PsAGS (mutant)<br />
**[[2lvx]] – fyAGS 2 MRH domain – fission yeast - NMR<br />
**[[2n1h]] – fyAGS 2 MRH domain (mutant) - NMR<br />
**[[7t6w]] – CtAGS – ''Chaetonium thermophilum''<br />
**[[7t6w]] – CtAGS – ''Chaetonium thermophilum''<br />
**[[7d9b]] – WcAGS – ''Weissella cibaria''<br />
**[[7d9b]] – WcAGS – ''Weissella cibaria''<br />
**[[8t7z]] – AGS – ''Klebsiella aerogenes''<br />


*α-glucosidase complex
*α-glucosidase complex


**[[5hjr]], [[7l9e]] – mAGS + glucosidase subunit beta - mouse<br />
**[[4xqm]] – fyAGS 2 MRH domain + mannose<br />
**[[7k9o]], [[7k9t]], [[7kbj]], [[7kbr]] – mAGS + glucosidase subunit beta + inhibitor<br />
**[[2jke]] – BtAGS + deoxynojirimycin<br />
**[[2jke]] – BtAGS + deoxynojirimycin<br />
**[[2jkp]] – BtAGS + castasnospermine<br />
**[[2jkp]] – BtAGS + castasnospermine<br />
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**[[5hqb]] – PaAGS (mutant) + panose <br />
**[[5hqb]] – PaAGS (mutant) + panose <br />
**[[1lf9]] – TtAGS + acarbose<br />
**[[1lf9]] – TtAGS + acarbose<br />
**[[8yie]] – AGS + acarbose – Arthrobacter gobiformis<br />
**[[1gai]], [[1gah]], [[1agm]] – AaAGS + acarbose<br />
**[[1gai]], [[1gah]], [[1agm]] – AaAGS + acarbose<br />
**[[2f6d]] – SfAGS + acarbose<br />
**[[2f6d]] – SfAGS + acarbose<br />
**[[1dog]] – AaAGS + deoxynojirimycin<br />
**[[1dog]] – AaAGS + deoxynojirimycin<br />
**[[1acz]], [[1ac0]] – AGS starch-binding domain + cyclodextrin - NMR<br />
**[[1acz]], [[1ac0]] – AGS starch-binding domain + cyclodextrin - NMR<br />
**[[5h9o]] – mAGS + glucose<br />
**[[5hjo]] – mAGS + substrate analog<br />
**[[5h9r]] – mAGS + intermediate<br />
**[[5ied]], [[5iee]], [[5ief]], [[5ieg]] – mAGS + iminosugar antiviral<br />
**[[3wy2]] – HaAGS + glucose<br />
**[[3wy3]] – HaAGS (mutant) + glucose<br />
**[[3wy4]] – HaAGS (mutant) + maltose<br />
**[[4xpp]] – PsAGS + galactose<br />
**[[4xpq]] – PsAGS + fucose<br />
**[[4xps]] – PsAGS (mutant) + galactpiranoside<br />
**[[3wel]], [[3wem]], [[3wen]], [[3weo]], [[3w37]] – bAGS + substrate<br />
**[[4xqm]] – fyAGS 2 MRH domain + mannose<br />
**[[5zcc]] – GeAGS (mutant) + maltose<br />
**[[5zcc]] – GeAGS (mutant) + maltose<br />
**[[5zcd]] – GeAGS (mutant) + maltotriose<br />
**[[5zcd]], [[8ibk]], [[8ids]] – GeAGS (mutant) + maltotriose<br />
**[[5zce]] – GeAGS (mutant) + maltotetraose<br />
**[[5zce]] – GeAGS (mutant) + maltotetraose<br />
**[[7d9c]], [[7dch]], [[7ehh]], [[7ehi]] – WcAGS + carbohydrate<br />
**[[7d9c]], [[7dch]], [[7ehh]], [[7ehi]] – WcAGS + carbohydrate<br />
**[[7r6j]], [[7rev]], [[7t66]], [[7t68]], [[7t8v]] – CtAGS + inhibitor <br />
**[[7r6j]], [[7rd2]], [[7rev]], [[7t66]], [[7t68]], [[7t8v]], [[8e3j]], [[8e3p]], [[8e4k]], [[8e5u]], [[8e6g]], [[8ecw]], [[8egv]], [[8ehp]], [[8eid]], [[8ekn]], [[8ele]], [[8epo]], [[8epr]], [[8eq7]], [[8eqx]], [[8er4]], [[8eud]], [[8eur]], [[8eut]], [[8eux]] – CtAGS + inhibitor <br />
 
*Lyosomal acid-alpha-glucosidase
 
**[[3ton]], [[5kzw]], [[5kzx]], [[5nn3]], [[5nn4]] – hAGS C-terminal - human<br />
**[[5nn8]] – hAGS + acarbose <br />
**[[7p2z]], [[7p32]], [[8cb1]] – hAGS + inhibitor <br />
**[[8cb6]] – hAGS + probe <br />
**[[5nn5]], [[5nn6]] – hAGS + jiromycin derivative<br />
 
*Neutral alpha-glucosidase
 
**[[8d43]], [[8emr]] – hAGS + glucosidase 2 subunit beta – Cryo EM<br />
**[[5f0e]], [[7l9e]] – mAGS + glucosidase subunit beta - mouse<br />
**[[5ied]], [[5iee]], [[5ief]], [[5ieg]] – mAGS + glucosidase subunit beta + inhibitor<br />
**[[7jty]], [[7k9n]], [[7k9o]], [[7k9q]], [[7k9t]], [[7kad]], [[7kb6]], [[7kb8]], [[7kbj]], [[7kbr]], [[7kry]] – mAGS (mutant) + glucosidase subunit beta + inhibitor<br />
**[[5hjo]] – mAGS + glucosidase subunit beta + substrate analog<br />
**[[5hjr]] – mAGS + glucosidase subunit beta + intermediate<br />
**[[5h9o]] – mAGS + glucosidase subunit beta + glucose<br />


*Alpha-glucosidase YIHQ
*Alpha-glucosidase YIHQ
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*Maltase  
*Maltase  


**[[3ton]], [[5kzw]], [[5kzx]], [[5nn3]], [[5nn4]]  – hAGS C-terminal - human<br />
**[[5nn8]] – hAGS + acarbose <br />
**[[3top]] – hAGS C-terminal + acarbose <br />
**[[3top]] – hAGS C-terminal + acarbose <br />
**[[3l4y]], [[3l4z]], [[3l4x]], [[3l4w]], [[3l4v]], [[3l4u]], [[3l4t]] – hAGS N-terminal + inhibitor<br />
**[[3l4y]], [[3l4z]], [[3l4x]], [[3l4w]], [[3l4v]], [[3l4u]], [[3l4t]] – hAGS N-terminal + inhibitor<br />
**[[5nn5]], [[5nn6]] – hAGS + jiromycin derivative<br />
**[[3w37]] – bAGS + acarbose <br />
**[[3w37]] – bAGS + acarbose <br />
**[[3wel]], [[3wem]], [[3wen]], [[3weo]] – bAGS + acarviosyl-maltooligosaccharide <br />
**[[3wel]], [[3wem]], [[3wen]], [[3weo]] – bAGS + acarviosyl-maltooligosaccharide <br />
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*Maltodextrin glucosidase  
*Maltodextrin glucosidase  


**[[5bn7]] – EcAGS <br />
**[[5bn7]], [[7vt9]] – EcAGS <br />
 
*Acid-alpha glucosidase
 
**[[7p2z]], [[7p32]] – hGAA + inhibitor <br />


*6-phospho-α-glucosidase  
*6-phospho-α-glucosidase  
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*Glucan 1,4-alpha glucosidase or glucoamylase
*Glucan 1,4-alpha glucosidase or glucoamylase


**[[6frv]] – AnGAGS catalytic domain residues 25-640<br />
**[[6frv]] – AnGAGS catalytic domain residues 25-640<br />

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Michal Harel
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