8ju3: Difference between revisions

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-'''Unreleased structure'''
-The entry 8ju3 is ON HOLD  until 2025-06-24
+==Mu phage tail fiber==
+<StructureSection load='8ju3' size='340' side='right'caption='[[8ju3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8ju3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_Mu Escherichia phage Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JU3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ju3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ju3 OCA], [https://pdbe.org/8ju3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ju3 RCSB], [https://www.ebi.ac.uk/pdbsum/8ju3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ju3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/S1_BPMU S1_BPMU] Component of the tail fiber that acts as receptor binding protein. Binds to the primary receptor, thereby determining the host range. Two alternate tail fiber S and S' proteins are encoded extending the host range of the virus.<ref>PMID:6250048</ref> [https://www.uniprot.org/uniprot/S2_BPMU S2_BPMU] Component of the tail fiber that acts as a receptor binding protein. Binds to the primary receptor, thereby determining the host range. Two alternate tail fiber S and S' proteins are encoded extending the host range of the virus.
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Bacteriophage Mu is a temperate phage known to infect various species of Enterobacteria, playing a role in bacterial mutation induction and horizontal gene transfer. The phage possesses two types of tail fibers important for host recognition, which enable it to expand its range of hosts. The alternate tail fibers are formed through the action of genes 49-50 or 52-51, allowing the Mu phage to recognize different surfaces of host cells. In a previous study, we presented the X-ray crystal structure of the C-terminal lipopolysaccharide (LPS)-binding domain of gene product (gp) 49, one of the subunits comprising the Mu tail fiber. In this study, we have determined the structure of the alternative tail fiber subunit, gp52, and compared it with other tail fibers. The results revealed that Mu phage employs different structural motifs for two individual tail fibers for recognizing different hosts.
-Authors: Yamashita, E., Takeda, S.
+Determination of the three-dimensional structure of bacteriophage Mu(-) tail fiber and its characterization.,Mori Y, Yamashita E, Nakagawa A, Matsuzawa T, Inagaki M, Aiba Y, Tanaka S, Hatori S, Ayami M, Takeda S Virology. 2024 May;593:110017. doi: 10.1016/j.virol.2024.110017. Epub 2024 Feb , 13. PMID:38382161<ref>PMID:38382161</ref>
-Description: Mu phage tail fiber
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
-[[Category: Yamashita, E]]
+<div class="pdbe-citations 8ju3" style="background-color:#fffaf0;"></div>
-[[Category: Takeda, S]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Escherichia phage Mu]]
+[[Category: Large Structures]]
+[[Category: Takeda S]]
+[[Category: Yamashita E]]