Bone morphogenetic protein: Difference between revisions
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== Function == | == Function == | ||
'''Bone morphogenetic protein''' (BMP) are growth factors which can induce formation of bone and cartllage'<ref>PMID:19900831</ref>. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. | '''Bone morphogenetic protein''' (BMP) are growth factors which can induce formation of bone and cartllage'<ref>PMID:19900831</ref>. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. | ||
*'''BMP-1''' cleaves the C-propeptides of type I pro collagen during the synthesis of extracellular collagen fibrils<ref>PMID:12637537</ref>. | |||
*'''BMP-2''' has important role in embryogenesis, bone formation and homeostasis<ref>PMID:32933207</ref>. | |||
*'''BMP-3''' is a major component in osteogenin<ref>PMID:11263666</ref>. | |||
*'''BMP-6''' is essential for expression of hepcidin which controls iron homeostasis<ref>PMID:34740612</ref>. | |||
*'''BMP-7''' is a major role in embryogenesis, skeletal morphogenesis and neurogenesis<ref>PMID:31979268</ref>. For details on '''BMP-7''' see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. | |||
*'''BMP-9''', '''BMP-11''' and '''Placental BMP-15''' see [[Growth differentiation factor]] | |||
*'''BMP-10''' is cardiac-specific inducing trophoblast differentiation in stem cells<ref>PMID:24070570</ref>. | |||
See also | |||
*[[Growth factors]], | |||
*[[Enzyme-linked receptor]] | |||
*[[Growth differentiation factor]] | |||
*[[TGF beta signaling pathway]]. | |||
== Relevance == | == Relevance == | ||