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==Inactive conformation of EGFR (T790M/V948R) kinase in complex with BI-4020== | ==Inactive conformation of EGFR (T790M/V948R) kinase in complex with BI-4020== | ||
<StructureSection load='7ky0' size='340' side='right'caption='[[7ky0]]' scene=''> | <StructureSection load='7ky0' size='340' side='right'caption='[[7ky0]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KY0 FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KY0 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ky0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ky0 OCA], [https://pdbe.org/7ky0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ky0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ky0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ky0 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XA4:(20R)-10,15,20-trimethyl-2-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-15H,17H-12,8-(metheno)pyrazolo[3,4 2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-7(6H)-one'>XA4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ky0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ky0 OCA], [https://pdbe.org/7ky0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ky0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ky0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ky0 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
==See Also== | |||
*[[Epidermal growth factor receptor 3D structures|Epidermal growth factor receptor 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 22:36, 29 May 2024
Inactive conformation of EGFR (T790M/V948R) kinase in complex with BI-4020Inactive conformation of EGFR (T790M/V948R) kinase in complex with BI-4020
Structural highlights
See Also |
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