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==Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, Se-dGTP and Calcium==
==Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus with duplex DNA, Se-dGTP and Calcium==
<StructureSection load='4dsi' size='340' side='right' caption='[[4dsi]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4dsi' size='340' side='right'caption='[[4dsi]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dsi]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DSI FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dsi]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DSI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ht3|3ht3]], [[4dsj|4dsj]], [[4dsk|4dsk]], [[4dsl|4dsl]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DGP:2-DEOXYGUANOSINE-5-MONOPHOSPHATE'>DGP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DPO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 Geobacillus stearothermophilus])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dsi OCA], [https://pdbe.org/4dsi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dsi RCSB], [https://www.ebi.ac.uk/pdbsum/4dsi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dsi ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dsi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dsi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dsi RCSB], [http://www.ebi.ac.uk/pdbsum/4dsi PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/E1C9K5_GEOSE E1C9K5_GEOSE]


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: DNA-directed DNA polymerase]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Abdur, R]]
[[Category: Large Structures]]
[[Category: Caton-Willians, J]]
[[Category: Abdur R]]
[[Category: Gan, J H]]
[[Category: Caton-Willians J]]
[[Category: Huang, Z]]
[[Category: Gan JH]]
[[Category: Liu, H H]]
[[Category: Huang Z]]
[[Category: Sheng, J]]
[[Category: Liu HH]]
[[Category: Soares, A S]]
[[Category: Sheng J]]
[[Category: Base stacking]]
[[Category: Soares AS]]
[[Category: Blunt end extension]]
[[Category: Calcium cation]]
[[Category: Dna polymerase]]
[[Category: Dna synthesis]]
[[Category: Polymerization fidelity]]
[[Category: Purine selectivity]]
[[Category: Transferase-dna complex]]

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