2yro: Difference between revisions

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New page: left|200px<br /><applet load="2yro" size="350" color="white" frame="true" align="right" spinBox="true" caption="2yro" /> '''Solution structure of the C-terminal Gal-bin...
 
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[[Image:2yro.jpg|left|200px]]<br /><applet load="2yro" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2yro" />
'''Solution structure of the C-terminal Gal-bind lectin protein from Human Galectin-8'''<br />


==About this Structure==
==Solution structure of the C-terminal Gal-bind lectin protein from Human Galectin-8==
2YRO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YRO OCA].  
<StructureSection load='2yro' size='340' side='right'caption='[[2yro]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2yro]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YRO FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yro OCA], [https://pdbe.org/2yro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yro RCSB], [https://www.ebi.ac.uk/pdbsum/2yro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yro ProSAT], [https://www.topsan.org/Proteins/RSGI/2yro TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yr/2yro_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yro ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Galectin 3D structures|Galectin 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: gal-bind lectin]]
[[Category: galectin]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: sugar binding]]
[[Category: sugar binding protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 13 08:22:06 2008''

Latest revision as of 22:16, 29 May 2024

Solution structure of the C-terminal Gal-bind lectin protein from Human Galectin-8Solution structure of the C-terminal Gal-bind lectin protein from Human Galectin-8

Structural highlights

2yro is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

LEG8_HUMAN Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925
Drag the structure with the mouse to rotate

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