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==Solution structure of S. aureus PrsA-PPIase==
==Solution structure of S. aureus PrsA-PPIase==
<StructureSection load='2jzv' size='340' side='right' caption='[[2jzv]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
<StructureSection load='2jzv' size='340' side='right'caption='[[2jzv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2jzv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JZV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JZV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2jzv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JZV FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">prsA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jzv OCA], [https://pdbe.org/2jzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jzv RCSB], [https://www.ebi.ac.uk/pdbsum/2jzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jzv ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jzv OCA], [http://pdbe.org/2jzv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jzv RCSB], [http://www.ebi.ac.uk/pdbsum/2jzv PDBsum]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PRSA_STAAM PRSA_STAAM]] Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity).  
[https://www.uniprot.org/uniprot/PRSA_STAAM PRSA_STAAM] Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jz/2jzv_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jz/2jzv_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jzv ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Peptidylprolyl isomerase]]
[[Category: Large Structures]]
[[Category: Heikkinen, S]]
[[Category: Kontinen, V]]
[[Category: Koskela, H]]
[[Category: Permi, P]]
[[Category: Seppala, R]]
[[Category: Tossavainen, H]]
[[Category: Foldase]]
[[Category: Isomerase]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Palmitate]]
[[Category: Parvulin]]
[[Category: Ppiase]]
[[Category: Proline isomerase]]
[[Category: Rotamase]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Heikkinen S]]
[[Category: Kontinen V]]
[[Category: Koskela H]]
[[Category: Permi P]]
[[Category: Seppala R]]
[[Category: Tossavainen H]]

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