2jw8: Difference between revisions

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 ==Solution structure of stereo-array isotope labelled (SAIL) C-terminal dimerization domain of SARS coronavirus nucleocapsid protein==
-<StructureSection load='2jw8' size='340' side='right' caption='[[2jw8]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='2jw8' size='340' side='right'caption='[[2jw8]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2jw8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cvhsa Cvhsa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JW8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JW8 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2jw8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome-related_coronavirus Severe acute respiratory syndrome-related coronavirus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JW8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JW8 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jw8 OCA], [http://pdbe.org/2jw8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jw8 RCSB], [http://www.ebi.ac.uk/pdbsum/2jw8 PDBsum]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jw8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jw8 OCA], [https://pdbe.org/2jw8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jw8 RCSB], [https://www.ebi.ac.uk/pdbsum/2jw8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jw8 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/NCAP_CVHSA NCAP_CVHSA]] Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid (By similarity).
+[https://www.uniprot.org/uniprot/NCAP_SARS NCAP_SARS] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication (PubMed:17210170). May modulate transforming growth factor-beta signaling by binding host SMAD3 (PubMed:18055455).[HAMAP-Rule:MF_04096]<ref>PMID:17210170</ref> <ref>PMID:18055455</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/2jw8_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jw/2jw8_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jw8 ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 28: / Line 30: @@
 ==See Also==
-*[[Nucleoprotein|Nucleoprotein]]
+*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Cvhsa]]
+[[Category: Large Structures]]
-[[Category: Chang, C]]
+[[Category: Severe acute respiratory syndrome-related coronavirus]]
-[[Category: Chang, Y]]
+[[Category: Chang C]]
-[[Category: Guntert, P]]
+[[Category: Chang Y]]
-[[Category: Hsu, Y]]
+[[Category: Guntert P]]
-[[Category: Huang, T]]
+[[Category: Hsu Y]]
-[[Category: Ikeya, T]]
+[[Category: Huang T]]
-[[Category: Kainosho, M]]
+[[Category: Ikeya T]]
-[[Category: Takeda, M]]
+[[Category: Kainosho M]]
-[[Category: Golgi apparatus]]
+[[Category: Takeda M]]
-[[Category: Nucleocapsid packaging]]
-[[Category: Phosphorylation]]
-[[Category: Rna-binding]]
-[[Category: Sail]]
-[[Category: Sars coronavirus nucleocapsid protein]]
-[[Category: Structural protein]]
-[[Category: Viral nucleoprotein]]
-[[Category: Viral protein]]
-[[Category: Virion]]