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==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==
==REFINED SOLUTION STRUCTURE OF THE TYR 41--> HIS MUTANT OF THE M13 GENE V PROTEIN. A COMPARISON WITH THE CRYSTAL STRUCTURE==
<StructureSection load='2gva' size='340' side='right' caption='[[2gva]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='2gva' size='340' side='right'caption='[[2gva]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2gva]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpm13 Bpm13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gva 1gva]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GVA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2gva]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_M13 Escherichia virus M13]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1gva 1gva]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GVA FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gvb|2gvb]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gva OCA], [http://pdbe.org/2gva PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2gva RCSB], [http://www.ebi.ac.uk/pdbsum/2gva PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gva OCA], [https://pdbe.org/2gva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gva RCSB], [https://www.ebi.ac.uk/pdbsum/2gva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gva ProSAT]</span></td></tr>
</table>
</table>
{{Large structure}}
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13]] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.  
[https://www.uniprot.org/uniprot/G5P_BPM13 G5P_BPM13] Binds to DNA in a highly cooperative manner without pronounced sequence specificity. During synthesis of the single-stranded (progeny) viral DNA, prevents the conversion into the double-stranded replicative form. G5P is displaced by the capsid protein G8P during phage assembly on the inner bacterial membrane.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gva_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/2gva_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Single-stranded DNA-binding protein|Single-stranded DNA-binding protein]]
*[[Single-stranded DNA-binding protein 3D structures|Single-stranded DNA-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bpm13]]
[[Category: Escherichia virus M13]]
[[Category: Folkers, P J.M]]
[[Category: Large Structures]]
[[Category: Folmer, R H.A]]
[[Category: Folkers PJM]]
[[Category: Hilbers, C W]]
[[Category: Folmer RHA]]
[[Category: Konings, R N.H]]
[[Category: Hilbers CW]]
[[Category: Nilges, M]]
[[Category: Konings RNH]]
[[Category: Prompers, J J]]
[[Category: Nilges M]]
[[Category: Prompers JJ]]

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