2gow: Difference between revisions

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-[[Image:2gow.png|left|200px]]
-{{STRUCTURE_2gow|  PDB=2gow  |  SCENE=  }}
+==Solution structure of BC059385 from Homo sapiens==
+<StructureSection load='2gow' size='340' side='right'caption='[[2gow]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2gow]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GOW FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gow FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gow OCA], [https://pdbe.org/2gow PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gow RCSB], [https://www.ebi.ac.uk/pdbsum/2gow PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gow ProSAT], [https://www.topsan.org/Proteins/CESG/2gow TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/UBL3_HUMAN UBL3_HUMAN]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/2gow_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gow ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The protein Bc059385, whose solution structure is reported here, is the human representative of a recently identified family of membrane-anchored ubiquitin-fold (MUB) proteins. Analysis of their similarity to ubiquitin indicates that homologous amino acid residues in MUBs form a hydrophobic surface very similar to the recognition patch surrounding Ile-44 in ubiquitin. This suggests that MUBs may interact with proteins containing an alpha-helical motif similar to those of some ubiquitin binding domains. A disordered loop common to MUBs may also provide a second protein interaction site. From the available data, it is probable that this protein is prenylated and associated with the membrane. With &lt;20% identity to ubiquitin, the MUB family further expands the sequence space that maps to the beta-grasp fold, and adds membrane localization to its list of functional roles.
-===Solution structure of BC059385 from Homo sapiens===
+Solution structure of a membrane-anchored ubiquitin-fold (MUB) protein from Homo sapiens.,de la Cruz NB, Peterson FC, Lytle BL, Volkman BF Protein Sci. 2007 Jul;16(7):1479-84. Epub 2007 Jun 13. PMID:17567738<ref>PMID:17567738</ref>
-{{ABSTRACT_PUBMED_17567738}}
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-==About this Structure==
+<div class="pdbe-citations 2gow" style="background-color:#fffaf0;"></div>
-[[2gow]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GOW OCA].
+== References ==
+<references/>
-==Reference==
+__TOC__
-<ref group="xtra">PMID:017567738</ref><references group="xtra"/>
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
+[[Category: Large Structures]]
-[[Category: Cruz, N B.de la.]]
+[[Category: Lytle BL]]
-[[Category: Lytle, B L.]]
+[[Category: Peterson FC]]
-[[Category: Peterson, F C.]]
+[[Category: Volkman BF]]
-[[Category: Volkman, B F.]]
+[[Category: De la Cruz NB]]
-[[Category: Bc059385]]
-[[Category: Center for eukaryotic structural genomic]]
-[[Category: Cesg]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: Unknown function]]