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==Solution structure of SH3 domain in Rho-GTPase-activating protein 4== | ==Solution structure of SH3 domain in Rho-GTPase-activating protein 4== | ||
<StructureSection load='2epd' size='340' side='right' caption='[[2epd | <StructureSection load='2epd' size='340' side='right'caption='[[2epd]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2epd]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2epd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EPD FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2epd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2epd OCA], [https://pdbe.org/2epd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2epd RCSB], [https://www.ebi.ac.uk/pdbsum/2epd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2epd ProSAT], [https://www.topsan.org/Proteins/RSGI/2epd TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/RHG04_HUMAN RHG04_HUMAN] Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 21: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Rho GTPase activating protein|Rho GTPase activating protein]] | *[[Rho GTPase activating protein 3D structures|Rho GTPase activating protein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Inoue M]] | ||
[[Category: | [[Category: Kigawa T]] | ||
[[Category: | [[Category: Muto Y]] | ||
[[Category: Shirouzu | [[Category: Shirouzu M]] | ||
[[Category: Tanabe | [[Category: Tanabe W]] | ||
[[Category: Terada | [[Category: Terada T]] | ||
[[Category: Tsuda | [[Category: Tsuda K]] | ||
[[Category: Yokoyama | [[Category: Yokoyama S]] | ||
Latest revision as of 21:54, 29 May 2024
Solution structure of SH3 domain in Rho-GTPase-activating protein 4Solution structure of SH3 domain in Rho-GTPase-activating protein 4
Structural highlights
FunctionRHG04_HUMAN Inhibitory effect on stress fiber organization. May down-regulate Rho-like GTPase in hematopoietic cells. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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