2eof: Difference between revisions

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[[Image:2eof.jpg|left|200px]]<br /><applet load="2eof" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2eof" />
'''Solution structure of the C2H2 type zinc finger (region 411-441) of human Zinc finger protein 268'''<br />


==About this Structure==
==Solution structure of the C2H2 type zinc finger (region 411-441) of human Zinc finger protein 268==
2EOF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOF OCA].  
<StructureSection load='2eof' size='340' side='right'caption='[[2eof]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2eof]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EOF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eof OCA], [https://pdbe.org/2eof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eof RCSB], [https://www.ebi.ac.uk/pdbsum/2eof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eof ProSAT], [https://www.topsan.org/Proteins/RSGI/2eof TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZN268_HUMAN ZN268_HUMAN] May be involved in transcriptional regulation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/2eof_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eof ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Abe, H.]]
[[Category: Abe H]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Kobayashi, N.]]
[[Category: Kobayashi N]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Li, H.]]
[[Category: Li H]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Saito K]]
[[Category: Saito, K.]]
[[Category: Sato M]]
[[Category: Sato, M.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: ZN]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nmr]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transcription]]
[[Category: zf-c2h2]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:13:35 2008''

Latest revision as of 21:53, 29 May 2024

Solution structure of the C2H2 type zinc finger (region 411-441) of human Zinc finger protein 268Solution structure of the C2H2 type zinc finger (region 411-441) of human Zinc finger protein 268

Structural highlights

2eof is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZN268_HUMAN May be involved in transcriptional regulation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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