2emw: Difference between revisions

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[[Image:2emw.jpg|left|200px]]<br /><applet load="2emw" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2emw" />
'''Solution structure of the C2H2 type zinc finger (region 301-331) of human Zinc finger protein 268'''<br />


==About this Structure==
==Solution structure of the C2H2 type zinc finger (region 301-331) of human Zinc finger protein 268==
2EMW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EMW OCA].  
<StructureSection load='2emw' size='340' side='right'caption='[[2emw]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2emw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EMW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2emw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2emw OCA], [https://pdbe.org/2emw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2emw RCSB], [https://www.ebi.ac.uk/pdbsum/2emw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2emw ProSAT], [https://www.topsan.org/Proteins/RSGI/2emw TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZN268_HUMAN ZN268_HUMAN] May be involved in transcriptional regulation.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/em/2emw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2emw ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Abe, H.]]
[[Category: Abe H]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Kobayashi, N.]]
[[Category: Kobayashi N]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Li, H.]]
[[Category: Li H]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Saito K]]
[[Category: Saito, K.]]
[[Category: Sato M]]
[[Category: Sato, M.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: ZN]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nmr]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transcription]]
[[Category: zf-c2h2]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 13:11:17 2008''

Latest revision as of 21:52, 29 May 2024

Solution structure of the C2H2 type zinc finger (region 301-331) of human Zinc finger protein 268Solution structure of the C2H2 type zinc finger (region 301-331) of human Zinc finger protein 268

Structural highlights

2emw is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZN268_HUMAN May be involved in transcriptional regulation.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

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