2ehe: Difference between revisions

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[[Image:2ehe.jpg|left|200px]]<br /><applet load="2ehe" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ehe" />
'''Solution structure of the first LIM domain from human four and a half LIM domains protein 3'''<br />


==Disease==
==Solution structure of the first LIM domain from human four and a half LIM domains protein 3==
Known disease associated with this structure: Hemophagocytic lymphohistiocytosis, familial, 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608897 608897]]
<StructureSection load='2ehe' size='340' side='right'caption='[[2ehe]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ehe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EHE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ehe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ehe OCA], [https://pdbe.org/2ehe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ehe RCSB], [https://www.ebi.ac.uk/pdbsum/2ehe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ehe ProSAT], [https://www.topsan.org/Proteins/RSGI/2ehe TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FHL3_HUMAN FHL3_HUMAN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eh/2ehe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ehe ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
2EHE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EHE OCA].
*[[Muscle LIM protein|Muscle LIM protein]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Inoue, K.]]
[[Category: Inoue K]]
[[Category: Nagashima, T.]]
[[Category: Nagashima T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: ZN]]
[[Category: fhl-3]]
[[Category: fhl3]]
[[Category: four and a half lim domains protein 3]]
[[Category: lim domain]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: skeletal muscle lim- protein 2]]
[[Category: slim 2]]
[[Category: slim2]]
[[Category: structural genomics]]
[[Category: structural protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:09:58 2008''

Latest revision as of 21:50, 29 May 2024

Solution structure of the first LIM domain from human four and a half LIM domains protein 3Solution structure of the first LIM domain from human four and a half LIM domains protein 3

Structural highlights

2ehe is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

FHL3_HUMAN

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

Drag the structure with the mouse to rotate

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