2ee1: Difference between revisions

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[[Image:2ee1.png|left|200px]]


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==Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4==
The line below this paragraph, containing "STRUCTURE_2ee1", creates the "Structure Box" on the page.
<StructureSection load='2ee1' size='340' side='right'caption='[[2ee1]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2ee1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EE1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ee1 OCA], [https://pdbe.org/2ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ee1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ee1 TOPSAN]</span></td></tr>
{{STRUCTURE_2ee1| PDB=2ee1 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/2ee1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ee1 ConSurf].
<div style="clear:both"></div>


===Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4===
==See Also==
 
*[[Chromodomain-helicase-DNA-binding protein 3D structures|Chromodomain-helicase-DNA-binding protein 3D structures]]
 
*[[Helicase 3D structures|Helicase 3D structures]]
==About this Structure==
== References ==
2EE1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE1 OCA].
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Harada, T.]]
[[Category: Large Structures]]
[[Category: Kigawa, T.]]
[[Category: Harada T]]
[[Category: Koshiba, S.]]
[[Category: Kigawa T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Koshiba S]]
[[Category: Sato, M.]]
[[Category: Sato M]]
[[Category: Tochio, N.]]
[[Category: Tochio N]]
[[Category: Watanabe, S.]]
[[Category: Watanabe S]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: Atp- dependent helicase chd4]]
[[Category: Chd-4]]
[[Category: Ec 3 6.1.-]]
[[Category: Mi-2 autoantigen 218 kda protein]]
[[Category: Mi2-beta]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 08:52:22 2009''

Latest revision as of 21:50, 29 May 2024

Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4

Structural highlights

2ee1 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

CHD4_HUMAN Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Tong JK, Hassig CA, Schnitzler GR, Kingston RE, Schreiber SL. Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex. Nature. 1998 Oct 29;395(6705):917-21. PMID:9804427 doi:http://dx.doi.org/10.1038/27699
  2. ↑ Sillibourne JE, Delaval B, Redick S, Sinha M, Doxsey SJ. Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity. Mol Biol Cell. 2007 Sep;18(9):3667-80. Epub 2007 Jul 11. PMID:17626165 doi:http://dx.doi.org/10.1091/mbc.E06-07-0604
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