2edf: Difference between revisions

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-[[Image:2edf.jpg|left|200px]]
- {{Structure
+==Solution structure of the second ig-like domain(2826-2915) from human Obscurin==
-|PDB= 2edf |SIZE=350|CAPTION= <scene name='initialview01'>2edf</scene>
+<StructureSection load='2edf' size='340' side='right'caption='[[2edf]]' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND=
+<table><tr><td colspan='2'>[[2edf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EDF FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-|GENE= OBSCN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2edf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edf OCA], [https://pdbe.org/2edf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2edf RCSB], [https://www.ebi.ac.uk/pdbsum/2edf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2edf ProSAT], [https://www.topsan.org/Proteins/RSGI/2edf TOPSAN]</span></td></tr>
-|DOMAIN=
+</table>
-|RELATEDENTRY=
+== Function ==
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2edf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edf OCA], [http://www.ebi.ac.uk/pdbsum/2edf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2edf RCSB]</span>
+[https://www.uniprot.org/uniprot/OBSCN_HUMAN OBSCN_HUMAN] Involved in myofibrillogenesis. Seems to be involved in assembly of myosin into sarcomeric A bands in striated muscle. Isoform 3 together with ANK1 isoform Mu17/Ank1.5 may provide a molecular link between the sarcoplasmic reticulum and myofibrils.<ref>PMID:11448995</ref> <ref>PMID:16205939</ref>
-}}
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/2edf_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2edf ConSurf].
+<div style="clear:both"></div>
-'''Solution structure of the second ig-like domain(2826-2915) from human Obscurin'''
+==See Also==
+*[[Obscurin|Obscurin]]
+== References ==
-==About this Structure==
+<references/>
-EDF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDF OCA].
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Hayashi, F.]]
+[[Category: Hayashi F]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Wakabayashi M]]
-[[Category: Wakabayashi, M.]]
+[[Category: Yokoyama S]]
-[[Category: Yokoyama, S.]]
+[[Category: Yoshida M]]
-[[Category: Yoshida, M.]]
+[[Category: Z-disk]]
-[[Category: beta-sandwich]]
-[[Category: contractile protein]]
-[[Category: ig-fold]]
-[[Category: national project on protein structural and functional analyse]]
-[[Category: nppsfa]]
-[[Category: obscurin-mlck]]
-[[Category: obscurin-myosin light chain kinase]]
-[[Category: obscurin-rhogef]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:47:24 2008''