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==Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)==
==Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)==
<StructureSection load='2ecc' size='340' side='right' caption='[[2ecc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ecc' size='340' side='right'caption='[[2ecc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ecc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ECC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ecc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ECC FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HOMEZ, KIAA1443 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ecc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecc OCA], [http://pdbe.org/2ecc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ecc RCSB], [http://www.ebi.ac.uk/pdbsum/2ecc PDBsum], [http://www.topsan.org/Proteins/RSGI/2ecc TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ecc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecc OCA], [https://pdbe.org/2ecc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ecc RCSB], [https://www.ebi.ac.uk/pdbsum/2ecc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ecc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ecc TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HOMEZ_HUMAN HOMEZ_HUMAN]] May function as a transcriptional regulator.  
[https://www.uniprot.org/uniprot/HOMEZ_HUMAN HOMEZ_HUMAN] May function as a transcriptional regulator.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ecc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ecc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Inoue, M]]
[[Category: Large Structures]]
[[Category: Kamatari, Y O]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kamatari YO]]
[[Category: Kobayashi, N]]
[[Category: Kigawa T]]
[[Category: Koshiba, S]]
[[Category: Kobayashi N]]
[[Category: Li, H]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K]]
[[Category: Li H]]
[[Category: Nameki, N]]
[[Category: Miyamoto K]]
[[Category: Ohnishi, S]]
[[Category: Nameki N]]
[[Category: Structural genomic]]
[[Category: Ohnishi S]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Dna binding protein]]
[[Category: Homeobox domain]]
[[Category: Homez]]
[[Category: Leucine zipper- containing factor]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription factor]]

Latest revision as of 21:49, 29 May 2024

Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)

Structural highlights

2ecc is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1wjh. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

HOMEZ_HUMAN May function as a transcriptional regulator.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
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