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==Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)==
==Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)==
<StructureSection load='2ecc' size='340' side='right' caption='[[2ecc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2ecc' size='340' side='right'caption='[[2ecc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ecc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ECC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ecc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ECC FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HOMEZ, KIAA1443 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ecc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecc OCA], [http://pdbe.org/2ecc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ecc RCSB], [http://www.ebi.ac.uk/pdbsum/2ecc PDBsum], [http://www.topsan.org/Proteins/RSGI/2ecc TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ecc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecc OCA], [https://pdbe.org/2ecc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ecc RCSB], [https://www.ebi.ac.uk/pdbsum/2ecc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ecc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ecc TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HOMEZ_HUMAN HOMEZ_HUMAN]] May function as a transcriptional regulator.  
[https://www.uniprot.org/uniprot/HOMEZ_HUMAN HOMEZ_HUMAN] May function as a transcriptional regulator.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ecc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ecc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ecc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Inoue, M]]
[[Category: Large Structures]]
[[Category: Kamatari, Y O]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kamatari YO]]
[[Category: Kobayashi, N]]
[[Category: Kigawa T]]
[[Category: Koshiba, S]]
[[Category: Kobayashi N]]
[[Category: Li, H]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K]]
[[Category: Li H]]
[[Category: Nameki, N]]
[[Category: Miyamoto K]]
[[Category: Ohnishi, S]]
[[Category: Nameki N]]
[[Category: Structural genomic]]
[[Category: Ohnishi S]]
[[Category: Tochio, N]]
[[Category: Tochio N]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Dna binding protein]]
[[Category: Homeobox domain]]
[[Category: Homez]]
[[Category: Leucine zipper- containing factor]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription factor]]

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