2ecc: Difference between revisions

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[[Image:2ecc.jpg|left|200px]]


{{Structure
==Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)==
|PDB= 2ecc |SIZE=350|CAPTION= <scene name='initialview01'>2ecc</scene>
<StructureSection load='2ecc' size='340' side='right'caption='[[2ecc]]' scene=''>
|SITE=
== Structural highlights ==
|LIGAND=
<table><tr><td colspan='2'>[[2ecc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wjh 1wjh]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ECC FirstGlance]. <br>
|ACTIVITY=
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= HOMEZ, KIAA1443 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ecc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ecc OCA], [https://pdbe.org/2ecc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ecc RCSB], [https://www.ebi.ac.uk/pdbsum/2ecc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ecc ProSAT], [https://www.topsan.org/Proteins/RSGI/2ecc TOPSAN]</span></td></tr>
}}
</table>
 
== Function ==
'''Solution Structure of the second Homeobox Domain of Human Homeodomain Leucine Zipper-Encoding Gene (Homez)'''
[https://www.uniprot.org/uniprot/HOMEZ_HUMAN HOMEZ_HUMAN] May function as a transcriptional regulator.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2ECC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1WJH. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ECC OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ec/2ecc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ecc ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kamatari, Y O.]]
[[Category: Kamatari YO]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Kobayashi, N.]]
[[Category: Kobayashi N]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Li, H.]]
[[Category: Li H]]
[[Category: Miyamoto, K.]]
[[Category: Miyamoto K]]
[[Category: Nameki, N.]]
[[Category: Nameki N]]
[[Category: Ohnishi, S.]]
[[Category: Ohnishi S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: homeobox domain]]
[[Category: homez]]
[[Category: leucine zipper- containing factor]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
[[Category: transcription factor]]
 
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