2ebr: Difference between revisions

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New page: left|200px<br /> <applet load="2ebr" size="450" color="white" frame="true" align="right" spinBox="true" caption="2ebr" /> '''Solution structure of the fourth zf-RanBP d...
 
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[[Image:2ebr.gif|left|200px]]<br />
<applet load="2ebr" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2ebr" />
'''Solution structure of the fourth zf-RanBP domain from human Nuclear pore complex protein Nup153'''<br />


==About this Structure==
==Solution structure of the fourth zf-RanBP domain from human Nuclear pore complex protein Nup153==
2EBR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2EBR OCA].  
<StructureSection load='2ebr' size='340' side='right'caption='[[2ebr]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ebr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EBR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ebr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ebr OCA], [https://pdbe.org/2ebr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ebr RCSB], [https://www.ebi.ac.uk/pdbsum/2ebr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ebr ProSAT], [https://www.topsan.org/Proteins/RSGI/2ebr TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NU153_HUMAN NU153_HUMAN] Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/2ebr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ebr ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Nagashima, T.]]
[[Category: Nagashima T]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Zhang HP]]
[[Category: Zhang, H.P.]]
[[Category: ZN]]
[[Category: 153 kda nucleoporin]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: nuclear pore complex protein]]
[[Category: nucleoporin nup153]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: transport protein]]
[[Category: zf-ranbp domain]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 21:48:00 2007''

Latest revision as of 21:48, 29 May 2024

Solution structure of the fourth zf-RanBP domain from human Nuclear pore complex protein Nup153Solution structure of the fourth zf-RanBP domain from human Nuclear pore complex protein Nup153

Structural highlights

2ebr is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

NU153_HUMAN Possible DNA-binding subunit of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

Drag the structure with the mouse to rotate

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