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[[Image:2doc.gif|left|200px]]<br /><applet load="2doc" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2doc" />
'''Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2'''<br />


==About this Structure==
==Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2==
2DOC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DOC OCA].  
<StructureSection load='2doc' size='340' side='right'caption='[[2doc]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2doc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DOC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2doc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2doc OCA], [https://pdbe.org/2doc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2doc RCSB], [https://www.ebi.ac.uk/pdbsum/2doc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2doc ProSAT], [https://www.topsan.org/Proteins/RSGI/2doc TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NCAM2_HUMAN NCAM2_HUMAN] May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/2doc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2doc ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: Yoneyama M]]
[[Category: Yoneyama, M.]]
[[Category: cell adhesion]]
[[Category: fn3 domain]]
[[Category: glycoprotein]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:00:55 2008''

Latest revision as of 21:45, 29 May 2024

Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2

Structural highlights

2doc is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

NCAM2_HUMAN May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA