2dng: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-[[Image:2dng.jpg|left|200px]]<br /><applet load="2dng" size="450" color="white" frame="true" align="right" spinBox="true"
-caption="2dng" />
-'''Solution structure of RNA binding domain in Eukaryotic translation initiation factor 4H'''<br />
-==About this Structure==
+==Solution structure of RNA binding domain in Eukaryotic translation initiation factor 4H==
-DNG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DNG OCA].
+<StructureSection load='2dng' size='340' side='right'caption='[[2dng]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2dng]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNG FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dng OCA], [https://pdbe.org/2dng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dng RCSB], [https://www.ebi.ac.uk/pdbsum/2dng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dng ProSAT], [https://www.topsan.org/Proteins/RSGI/2dng TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/IF4H_MOUSE IF4H_MOUSE] Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA (By similarity).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/2dng_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dng ConSurf].
+<div style="clear:both"></div>
+==See Also==
+*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Single protein]]
+[[Category: Inoue M]]
-[[Category: Inoue, M.]]
+[[Category: Kigawa T]]
-[[Category: Kigawa, T.]]
+[[Category: Muto Y]]
-[[Category: Muto, Y.]]
+[[Category: Shirouzu M]]
-[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
+[[Category: Terada T]]
-[[Category: Shirouzu, M.]]
+[[Category: Tsuda K]]
-[[Category: Terada, T.]]
+[[Category: Yokoyama S]]
-[[Category: Tsuda, K.]]
-[[Category: Yokoyama, S.]]
-[[Category: national project on protein structural and functional analyses]]
-[[Category: nppsfa]]
-[[Category: rbd]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rrm domain]]
-[[Category: rsgi]]
-[[Category: structural genomics ]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:41:03 2007''