2dmx: Difference between revisions

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==Solution structure of the J domain of DnaJ homolog subfamily B member 8==
==Solution structure of the J domain of DnaJ homolog subfamily B member 8==
<StructureSection load='2dmx' size='340' side='right'caption='[[2dmx]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2dmx' size='340' side='right'caption='[[2dmx]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2dmx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2dmx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DMX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DMX FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DNAJB8 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmx OCA], [https://pdbe.org/2dmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmx RCSB], [https://www.ebi.ac.uk/pdbsum/2dmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dmx TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dmx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dmx OCA], [https://pdbe.org/2dmx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dmx RCSB], [https://www.ebi.ac.uk/pdbsum/2dmx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dmx ProSAT], [https://www.topsan.org/Proteins/RSGI/2dmx TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DNJB8_HUMAN DNJB8_HUMAN]] Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.  
[https://www.uniprot.org/uniprot/DNJB8_HUMAN DNJB8_HUMAN] Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Inoue, M]]
[[Category: Inoue M]]
[[Category: Kigawa, T]]
[[Category: Kigawa T]]
[[Category: Koshiba, S]]
[[Category: Koshiba S]]
[[Category: Ohnishi, S]]
[[Category: Ohnishi S]]
[[Category: Structural genomic]]
[[Category: Tochio N]]
[[Category: Tochio, N]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S]]
[[Category: Chaperone]]
[[Category: Dnaj j domain]]
[[Category: Helix-turn-helix motif]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]

Latest revision as of 21:44, 29 May 2024

Solution structure of the J domain of DnaJ homolog subfamily B member 8Solution structure of the J domain of DnaJ homolog subfamily B member 8

Structural highlights

2dmx is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

DNJB8_HUMAN Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

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