1kwc: Difference between revisions

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==The His145Ala mutant of 2,3-dihydroxybiphenyl dioxygenase in complex with 2,3-dihydroxybiphenyl==
==The His145Ala mutant of 2,3-dihydroxybiphenyl dioxygenase in complex with 2,3-dihydroxybiphenyl==
<StructureSection load='1kwc' size='340' side='right' caption='[[1kwc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1kwc' size='340' side='right'caption='[[1kwc]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1kwc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pses1 Pses1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KWC FirstGlance]. <br>
<table><tr><td colspan='2'>[[1kwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._KKS102 Pseudomonas sp. KKS102]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KWC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BPY:BIPHENYL-2,3-DIOL'>BPY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kw3|1kw3]], [[1kw6|1kw6]], [[1kw8|1kw8]], [[1kw9|1kw9]], [[1kwb|1kwb]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BPY:BIPHENYL-2,3-DIOL'>BPY</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Biphenyl-2,3-diol_1,2-dioxygenase Biphenyl-2,3-diol 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.39 1.13.11.39] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwc OCA], [https://pdbe.org/1kwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kwc RCSB], [https://www.ebi.ac.uk/pdbsum/1kwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kwc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kwc OCA], [http://pdbe.org/1kwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kwc RCSB], [http://www.ebi.ac.uk/pdbsum/1kwc PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BPHC_PSES1 BPHC_PSES1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/1kwc_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/1kwc_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kwc ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
*[[Dioxygenase|Dioxygenase]]
*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Biphenyl-2,3-diol 1,2-dioxygenase]]
[[Category: Large Structures]]
[[Category: Pses1]]
[[Category: Pseudomonas sp. KKS102]]
[[Category: Fukuda, M]]
[[Category: Fukuda M]]
[[Category: Masai, E]]
[[Category: Masai E]]
[[Category: Nishizaki, T]]
[[Category: Nishizaki T]]
[[Category: Nonaka, T]]
[[Category: Nonaka T]]
[[Category: Sato, N]]
[[Category: Sato N]]
[[Category: Sazaki, G]]
[[Category: Sazaki G]]
[[Category: Senda, T]]
[[Category: Senda T]]
[[Category: Sugimoto, K]]
[[Category: Sugimoto K]]
[[Category: Takahashi, Y]]
[[Category: Takahashi Y]]
[[Category: Uragami, Y]]
[[Category: Uragami Y]]
[[Category: Four time repetitions of the beta-alpha-beta-beta-beta motif]]
[[Category: Oxidoreductase]]

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