Annexin: Difference between revisions
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[[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. Annexins divide into species and are numbered from I to XII. | [[Annexin|Annexins]] are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. Annexins divide into species and are numbered from I to XII. | ||
*'''Annexin I''' is involved in a variety of pathways. <br /> | *'''Annexin I''' is involved in a variety of pathways<ref>PMID:17215481</ref>. <br /> | ||
*'''Annexin V''' is the most abundant scaffolding <ref>PMID: | *'''Annexin II''' is involved in angiogenesis, tutor progression and metastasis<ref>PMID:18220793</ref>. See also [[Ezetimibe]].<br /><br /> | ||
*'''Annexin V''' is the most abundant scaffolding protein. <br /> | |||
*'''Annexin VI''' is involved in endocytosis and regulates entry of ligands to prelysosomal compartment<ref>PMID:10940299</ref>. <br /> | |||
*'''Annexin VIII''' is calcium-dependent phospholipid-binding involved in blood coagulation<ref>PMID:8018923</ref>. <br /> | |||
*'''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. <br /> | *'''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. <br /> | ||
*'''Annexin A-V''' has a major role in coagulation. <br /> | *'''Annexin A-V''' has a major role in coagulation. <br /> | ||
== Relevance == | == Relevance == | ||