Alpha-glucosidase: Difference between revisions

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== Function ==
== Function ==


'''Alpha glucosidase''' (AGS) or '''maltase''' breaks down the 1,4-α bonds in starch or disaccharides to produce glucose.  '''Maltase''' breaks down maltose.  '''Isomaltase''' breaks the 1,6 bond.<ref>PMID:18848471</ref> See also [[Kennedy research]].
'''Alpha glucosidase''' (AGS) or '''maltase''' breaks down the 1,4-α bonds in starch or disaccharides to produce glucose.  '''Maltase''' breaks down maltose.  '''Isomaltase''' or '''sucrase-isomaltase''' or '''oligo-1,6-glucosidase''' breaks the 1,6 bond.<ref>PMID:18848471</ref>
*'''Maltase-glucoamylase''' has important role in glucose production.  It hydrolize linear alpha-1,4-linked oligosaccharides<ref>PMID:22058037</ref>.<br />
*'''Acid-alpha gucosidase''' degrades glycogen polymers to glucose in the acidic lysosomes<ref>PMID:17217857</ref>.<br />
*'''6-phospho-alpha gucosidase''' hydrolyses maltose-6"-phosphate<ref>PMID:15341727</ref>.<br />
*'''Glucan 1,4-alpha gucosidase''' hydrolyses the terminal 1,4-linked alpha-D-glucose residues in polysaccharides to produce beta-glucose.<br />
For details see [[Sucrase-isomaltase]].
 
See also [[Kennedy research]] and [[Carbohydrate Metabolism]].


== Disease ==
== Disease ==

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Michal Harel, Alexander Berchansky