2cz1: Difference between revisions
New page: left|200px<br /><applet load="2cz1" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cz1, resolution 1.39Å" /> '''photo-activation sta... |
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== | ==photo-activation state of Fe-type NHase with n-BA in anaerobic condition== | ||
<StructureSection load='2cz1' size='340' side='right'caption='[[2cz1]], [[Resolution|resolution]] 1.39Å' scene=''> | |||
[[ | == Structural highlights == | ||
[[Category: | <table><tr><td colspan='2'>[[2cz1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ1 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz1 OCA], [https://pdbe.org/2cz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz1 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz1 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz1_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz1 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Nitrile hydratase|Nitrile hydratase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rhodococcus erythropolis]] | [[Category: Rhodococcus erythropolis]] | ||
[[Category: Endo | [[Category: Endo I]] | ||
[[Category: Hashimoto | [[Category: Hashimoto K]] | ||
[[Category: Kamiya | [[Category: Kamiya N]] | ||
[[Category: Kawano | [[Category: Kawano Y]] | ||
[[Category: Nakayama | [[Category: Nakayama H]] | ||
[[Category: Odaka | [[Category: Odaka M]] | ||
[[Category: Takio K]] | |||
[[Category: Takio | |||
