2cz0: Difference between revisions
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==photo-activation state of Fe-type NHase in aerobic condition== | |||
<StructureSection load='2cz0' size='340' side='right'caption='[[2cz0]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2cz0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz0 OCA], [https://pdbe.org/2cz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz0 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz0 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz0_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz0 ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[Nitrile hydratase|Nitrile hydratase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Large Structures]] | ||
[[Category: | |||
[[Category: Rhodococcus erythropolis]] | [[Category: Rhodococcus erythropolis]] | ||
[[Category: Endo | [[Category: Endo I]] | ||
[[Category: Hashimoto | [[Category: Hashimoto K]] | ||
[[Category: Kamiya | [[Category: Kamiya N]] | ||
[[Category: Kawano | [[Category: Kawano Y]] | ||
[[Category: Nakayama | [[Category: Nakayama H]] | ||
[[Category: Odaka | [[Category: Odaka M]] | ||
[[Category: Takio K]] | |||
[[Category: Takio | |||
Latest revision as of 14:32, 22 May 2024
photo-activation state of Fe-type NHase in aerobic conditionphoto-activation state of Fe-type NHase in aerobic condition
Structural highlights
FunctionNHAA_RHOER NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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