2cs5: Difference between revisions

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[[Image:2cs5.gif|left|200px]]


{{Structure
==Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4==
|PDB= 2cs5 |SIZE=350|CAPTION= <scene name='initialview01'>2cs5</scene>
<StructureSection load='2cs5' size='340' side='right'caption='[[2cs5]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2cs5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CS5 FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= PTPN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs5 OCA], [https://pdbe.org/2cs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cs5 RCSB], [https://www.ebi.ac.uk/pdbsum/2cs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cs5 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cs5 TOPSAN]</span></td></tr>
|DOMAIN=
</table>
|RELATEDENTRY=
== Function ==
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cs5 OCA], [http://www.ebi.ac.uk/pdbsum/2cs5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2cs5 RCSB]</span>
[https://www.uniprot.org/uniprot/PTN4_HUMAN PTN4_HUMAN] May act at junctions between the membrane and the cytoskeleton.
}}
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/2cs5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cs5 ConSurf].
<div style="clear:both"></div>


'''Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4'''
==See Also==
 
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2CS5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CS5 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Hayashi F]]
[[Category: Hayashi, F.]]
[[Category: Nagashima T]]
[[Category: Nagashima, T.]]
[[Category: Yokoyama S]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama, S.]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: pdz domain]]
[[Category: ptpase]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:25:43 2008''

Latest revision as of 14:30, 22 May 2024

Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4Solution structure of PDZ domain of Protein tyrosine phosphatase, non-receptor type 4

Structural highlights

2cs5 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

PTN4_HUMAN May act at junctions between the membrane and the cytoskeleton.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

Drag the structure with the mouse to rotate

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