2b5r: Difference between revisions

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 <StructureSection load='2b5r' size='340' side='right'caption='[[2b5r]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2b5r]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/As_4.1611 As 4.1611]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2B5R FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2b5r]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5R FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5r OCA], [https://pdbe.org/2b5r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5r RCSB], [https://www.ebi.ac.uk/pdbsum/2b5r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5r ProSAT], [https://www.topsan.org/Proteins/ISPC/2b5r TOPSAN]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2b5r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5r OCA], [http://pdbe.org/2b5r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2b5r RCSB], [http://www.ebi.ac.uk/pdbsum/2b5r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5r ProSAT], [http://www.topsan.org/Proteins/ISPC/2b5r TOPSAN]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/BLAT_ECOLX BLAT_ECOLX]] TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors. [[http://www.uniprot.org/uniprot/BLIP_STRCL BLIP_STRCL]] Inhibits a wide variety of beta lactamases.
+[https://www.uniprot.org/uniprot/BLIP_STRCL BLIP_STRCL] Inhibits a wide variety of beta lactamases.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
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 __TOC__
 </StructureSection>
-[[Category: Bacillus coli migula 1895]]
+[[Category: Escherichia coli]]
-[[Category: As 4 1611]]
-[[Category: Beta-lactamase]]
 [[Category: Large Structures]]
-[[Category: Albeck, S]]
+[[Category: Streptomyces clavuligerus]]
-[[Category: Dym, O]]
+[[Category: Albeck S]]
-[[Category: ISPC, Israel Structural Proteomics Center]]
+[[Category: Dym O]]
-[[Category: Meged, R]]
+[[Category: Meged R]]
-[[Category: Rahat, O]]
+[[Category: Rahat O]]
-[[Category: Screiber, G]]
+[[Category: Screiber G]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]
-[[Category: Protein-protein complex]]
-[[Category: Structural genomic]]