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[[Image:2apt.gif|left|200px]]<br /><applet load="2apt" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2apt, resolution 2.000&Aring;" />
'''Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain'''<br />


==About this Structure==
==Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain==
2APT is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=MLA:'>MLA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2APT OCA].  
<StructureSection load='2apt' size='340' side='right'caption='[[2apt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2apt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2APT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2APT FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2apt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2apt OCA], [https://pdbe.org/2apt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2apt RCSB], [https://www.ebi.ac.uk/pdbsum/2apt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2apt ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A2NAI0_RAT A2NAI0_RAT]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ap/2apt_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2apt ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
The nitty-gritty of protein interactions., Schreiber G, Structure. 2005 Dec;13(12):1737-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16338399 16338399]
*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
[[Category: Protein complex]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Cho, S.]]
[[Category: Cho S]]
[[Category: Guan, R.]]
[[Category: Guan R]]
[[Category: Kerzic, M C.]]
[[Category: Kerzic MC]]
[[Category: Kieke, M C.]]
[[Category: Kieke MC]]
[[Category: Kranz, D M.]]
[[Category: Kranz DM]]
[[Category: Mariuzza, R A.]]
[[Category: Mariuzza RA]]
[[Category: Sundberg, E J.]]
[[Category: Sundberg EJ]]
[[Category: Swaminathan, C P.]]
[[Category: Swaminathan CP]]
[[Category: Yang, J.]]
[[Category: Yang J]]
[[Category: MLA]]
[[Category: the murine t cell receptor v beta 8 2 domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:41 2008''

Latest revision as of 14:17, 22 May 2024

Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domainCrystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain

Structural highlights

2apt is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

A2NAI0_RAT

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2apt, resolution 2.00Å

Drag the structure with the mouse to rotate

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