7ft0: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 7ft0 is ON HOLD
+==SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z56767614==
+<StructureSection load='7ft0' size='340' side='right'caption='[[7ft0]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7ft0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FT0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FT0 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RWP:methyl+4-[(trifluoroacetyl)amino]benzoate'>RWP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ft0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ft0 OCA], [https://pdbe.org/7ft0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ft0 RCSB], [https://www.ebi.ac.uk/pdbsum/7ft0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ft0 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>
-Authors: Bradshaw, W.J., Katis, V.L., Bountra, C., von Delft, F., Brennan, P.E.
+==See Also==
+*[[3D structures of syntenin|3D structures of syntenin]]
-Description: SDCBP PanDDA analysis group deposition --The PDZ domans of SDCBP in complex with Z56767614
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Katis, V.L]]
+__TOC__
-[[Category: Von Delft, F]]
+</StructureSection>
-[[Category: Bountra, C]]
+[[Category: Homo sapiens]]
-[[Category: Brennan, P.E]]
+[[Category: Large Structures]]
-[[Category: Bradshaw, W.J]]
+[[Category: Bountra C]]
+[[Category: Bradshaw WJ]]
+[[Category: Brennan PE]]
+[[Category: Katis VL]]
+[[Category: Von Delft F]]