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==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==
==THE REFINED STRUCTURE OF BACTERIOPHAGE MS2 AT 2.8 ANGSTROMS RESOLUTION==
<StructureSection load='2ms2' size='340' side='right' caption='[[2ms2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2ms2' size='340' side='right'caption='[[2ms2]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteriophage_ms2 Bacteriophage ms2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ms2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ms2 1ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MS2 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [http://pdbe.org/2ms2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [http://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ms2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ms2 OCA], [https://pdbe.org/2ms2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ms2 RCSB], [https://www.ebi.ac.uk/pdbsum/2ms2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ms2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/COAT_BPMS2 COAT_BPMS2]] Forms the phage shell; binds to the phage RNA.  
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2ms2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ms2" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage ms2]]
[[Category: Escherichia phage MS2]]
[[Category: Liljas, L]]
[[Category: Large Structures]]
[[Category: Valegard, K]]
[[Category: Liljas L]]
[[Category: Bacteriophage coat protein]]
[[Category: Valegard K]]
[[Category: Icosahedral virus]]
[[Category: Virus]]

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