2lfb: Difference between revisions
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==HOMEODOMAIN FROM RAT LIVER LFB1/HNF1 TRANSCRIPTION FACTOR, NMR, 20 STRUCTURES== | ==HOMEODOMAIN FROM RAT LIVER LFB1/HNF1 TRANSCRIPTION FACTOR, NMR, 20 STRUCTURES== | ||
<StructureSection load='2lfb' size='340' side='right'caption='[[2lfb | <StructureSection load='2lfb' size='340' side='right'caption='[[2lfb]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2lfb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LFB FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfb OCA], [https://pdbe.org/2lfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lfb RCSB], [https://www.ebi.ac.uk/pdbsum/2lfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lfb ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lfb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfb OCA], [https://pdbe.org/2lfb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lfb RCSB], [https://www.ebi.ac.uk/pdbsum/2lfb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lfb ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/HNF1A_RAT HNF1A_RAT] Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Billeter | [[Category: Rattus rattus]] | ||
[[Category: Leiting | [[Category: Billeter M]] | ||
[[Category: Schott | [[Category: Leiting B]] | ||
[[Category: Wider | [[Category: Schott O]] | ||
[[Category: Wuthrich | [[Category: Wider G]] | ||
[[Category: Wuthrich K]] | |||