1suh: Difference between revisions

<StructureSection load='1suh' size='340' side='right'caption='[[1suh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[1suh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SUH OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1SUH FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">X06115 (GENBANK) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1suh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1suh OCA], [http://pdbe.org/1suh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1suh RCSB], [http://www.ebi.ac.uk/pdbsum/1suh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1suh ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity).  E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).  

[[Category: Lk3 transgenic mice]]

[[Category: Ikura, M]]

[[Category: Kay, C M]]

[[Category: Overduin, M]]

[[Category: Tong, K I]]

[[Category: Cell adhesion]]