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==The alternatively spliced PDZ2 domain of PTP-BL==
==The alternatively spliced PDZ2 domain of PTP-BL==
<StructureSection load='1ozi' size='340' side='right'caption='[[1ozi]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='1ozi' size='340' side='right'caption='[[1ozi]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ozi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OZI FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ozi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OZI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OZI FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gm1|1gm1]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTP-BL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ozi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ozi OCA], [https://pdbe.org/1ozi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ozi RCSB], [https://www.ebi.ac.uk/pdbsum/1ozi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ozi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ozi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ozi OCA], [https://pdbe.org/1ozi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ozi RCSB], [https://www.ebi.ac.uk/pdbsum/1ozi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ozi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PTN13_MOUSE PTN13_MOUSE]] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.  
[https://www.uniprot.org/uniprot/PTN13_MOUSE PTN13_MOUSE] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Aelen J]]
[[Category: Aelen, J]]
[[Category: Hendriks W]]
[[Category: Berk, L van den]]
[[Category: Oostendorp M]]
[[Category: Hendriks, W]]
[[Category: Vuister GW]]
[[Category: Oostendorp, M]]
[[Category: Walma T]]
[[Category: Vuister, G W]]
[[Category: Van den Berk L]]
[[Category: Walma, T]]
[[Category: Adenomatous polyposis coli]]
[[Category: All-beta protein]]
[[Category: Apc]]
[[Category: Hydrolase]]
[[Category: Interaction with c-termini]]
[[Category: Pdz domain]]
[[Category: Reversion induced lim]]
[[Category: Ril]]

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