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==SOLUTION STRUCTURE OF A SPECIFIC DNA COMPLEX OF THE MYB DNA-BINDING DOMAIN WITH COOPERATIVE RECOGNITION HELICES== | ==SOLUTION STRUCTURE OF A SPECIFIC DNA COMPLEX OF THE MYB DNA-BINDING DOMAIN WITH COOPERATIVE RECOGNITION HELICES== | ||
<StructureSection load='1mse' size='340' side='right'caption='[[1mse | <StructureSection load='1mse' size='340' side='right'caption='[[1mse]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1mse]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1mse]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSE FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mse OCA], [https://pdbe.org/1mse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mse RCSB], [https://www.ebi.ac.uk/pdbsum/1mse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mse ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mse FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mse OCA], [https://pdbe.org/1mse PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mse RCSB], [https://www.ebi.ac.uk/pdbsum/1mse PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mse ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Inoue | [[Category: Inoue T]] | ||
[[Category: Ishii | [[Category: Ishii S]] | ||
[[Category: Kanai | [[Category: Kanai H]] | ||
[[Category: Morikawa | [[Category: Morikawa S]] | ||
[[Category: Nakamura | [[Category: Nakamura H]] | ||
[[Category: Nishimura | [[Category: Nishimura Y]] | ||
[[Category: Ogata | [[Category: Ogata K]] | ||
[[Category: Sarai | [[Category: Sarai A]] | ||
[[Category: Sekikawa | [[Category: Sekikawa A]] | ||