1kzx: Difference between revisions
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==Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T)== | ==Solution structure of human intestinal fatty acid binding protein with a naturally-occurring single amino acid substitution (A54T)== | ||
<StructureSection load='1kzx' size='340' side='right'caption='[[1kzx | <StructureSection load='1kzx' size='340' side='right'caption='[[1kzx]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1kzx]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1kzx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KZX FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzx OCA], [https://pdbe.org/1kzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kzx RCSB], [https://www.ebi.ac.uk/pdbsum/1kzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzx ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/FABPI_HUMAN FABPI_HUMAN] FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Baier | [[Category: Baier LJ]] | ||
[[Category: Hamilton | [[Category: Hamilton JA]] | ||
[[Category: Luecke | [[Category: Luecke C]] | ||
[[Category: Sacchettini | [[Category: Sacchettini JC]] | ||
[[Category: Zhang | [[Category: Zhang F]] | ||