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==THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER==
==THE SOLUTION STRUCTURE AND DYNAMICS OF THE DNA BINDING DOMAIN OF HMG-D FROM DROSOPHILA MELANOGASTER==
<StructureSection load='1hma' size='340' side='right'caption='[[1hma]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1hma' size='340' side='right'caption='[[1hma]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1hma]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HMA FirstGlance]. <br>
<table><tr><td colspan='2'>[[1hma]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HMA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HMA FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hma OCA], [https://pdbe.org/1hma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hma RCSB], [https://www.ebi.ac.uk/pdbsum/1hma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hma ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hma FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hma OCA], [https://pdbe.org/1hma PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hma RCSB], [https://www.ebi.ac.uk/pdbsum/1hma PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hma ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/HMGD_DROME HMGD_DROME]] Binds preferentially single-stranded DNA and unwinds double stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1.<ref>PMID:1373803</ref> <ref>PMID:8168480</ref> <ref>PMID:7720717</ref>
[https://www.uniprot.org/uniprot/HMGD_DROME HMGD_DROME] Binds preferentially single-stranded DNA and unwinds double stranded DNA. Prefers sites containing the sequence 5'-ttg-3'. Facilitates DNA bending. Associated with early embryonic chromatin in the absence of histone H1.<ref>PMID:1373803</ref> <ref>PMID:8168480</ref> <ref>PMID:7720717</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Churchill, M E.A]]
[[Category: Churchill MEA]]
[[Category: Jones, D N.M]]
[[Category: Jones DNM]]
[[Category: Keeler, J]]
[[Category: Keeler J]]
[[Category: Ner, S S]]
[[Category: Ner SS]]
[[Category: Neuhaus, D]]
[[Category: Neuhaus D]]
[[Category: Searles, M A]]
[[Category: Searles MA]]
[[Category: Shaw, G L]]
[[Category: Shaw GL]]
[[Category: Travers, A A]]
[[Category: Travers AA]]
[[Category: Dna-binding]]

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