1fj7: Difference between revisions
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==SOLUTION STRUCTURE OF NUCLEOLIN RBD1== | ==SOLUTION STRUCTURE OF NUCLEOLIN RBD1== | ||
<StructureSection load='1fj7' size='340' side='right' caption='[[1fj7 | <StructureSection load='1fj7' size='340' side='right'caption='[[1fj7]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1fj7]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1fj7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesocricetus_auratus Mesocricetus auratus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FJ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FJ7 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fj7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fj7 OCA], [https://pdbe.org/1fj7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fj7 RCSB], [https://www.ebi.ac.uk/pdbsum/1fj7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fj7 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/NUCL_MESAU NUCL_MESAU] Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats (By similarity).<ref>PMID:3409881</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fj/1fj7_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fj/1fj7_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 1fj7" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1fj7" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Nucleolin|Nucleolin]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Allain | [[Category: Mesocricetus auratus]] | ||
[[Category: Bouvet | [[Category: Allain FH-T]] | ||
[[Category: Feigon | [[Category: Bouvet P]] | ||
[[Category: Gilbert | [[Category: Feigon J]] | ||
[[Category: Gilbert DE]] | |||