1dd7: Difference between revisions
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<StructureSection load='1dd7' size='340' side='right'caption='[[1dd7]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='1dd7' size='340' side='right'caption='[[1dd7]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1dd7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1dd7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DD7 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PM:METHYL+(3S)-3-{2-[(1,3-BENZODIOXOL-5-YLMETHYL)AMINO]-2-OXOETHYL}-4-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]PIPERAZINE-1-CARBOXYLATE'>1PM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO3:SULFITE+ION'>SO3</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PM:METHYL+(3S)-3-{2-[(1,3-BENZODIOXOL-5-YLMETHYL)AMINO]-2-OXOETHYL}-4-[2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL]PIPERAZINE-1-CARBOXYLATE'>1PM</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO3:SULFITE+ION'>SO3</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dd7 OCA], [https://pdbe.org/1dd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dd7 RCSB], [https://www.ebi.ac.uk/pdbsum/1dd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dd7 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dd7 OCA], [https://pdbe.org/1dd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dd7 RCSB], [https://www.ebi.ac.uk/pdbsum/1dd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dd7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NOS2_MOUSE NOS2_MOUSE] Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.<ref>PMID:16373578</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Adler | [[Category: Adler M]] | ||
[[Category: Whitlow | [[Category: Whitlow M]] | ||