1cfp: Difference between revisions

<StructureSection load='1cfp' size='340' side='right'caption='[[1cfp]]' scene=''>

<table><tr><td colspan='2'>[[1cfp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CFP FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cfp OCA], [https://pdbe.org/1cfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cfp RCSB], [https://www.ebi.ac.uk/pdbsum/1cfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cfp ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/S100B_BOVIN S100B_BOVIN] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization (By similarity).<ref>PMID:14661952</ref>  

[[Category: Bos taurus]]

[[Category: Kilby PM]]

[[Category: Roberts GCK]]

[[Category: Vaneldik LJ]]