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==NMR STRUCTURE OF THE CAD DOMAIN OF CASPASE-ACTIVATED DNASE==
==NMR STRUCTURE OF THE CAD DOMAIN OF CASPASE-ACTIVATED DNASE==
<StructureSection load='1c9f' size='340' side='right' caption='[[1c9f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1c9f' size='340' side='right'caption='[[1c9f]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1c9f]] is a 1 chain structure. The August 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Caspases''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_8 10.2210/rcsb_pdb/mom_2004_8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C9F FirstGlance]. <br>
<table><tr><td colspan='2'>[[1c9f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. The August 2004 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Caspases''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2004_8 10.2210/rcsb_pdb/mom_2004_8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C9F FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c9f OCA], [http://pdbe.org/1c9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c9f RCSB], [http://www.ebi.ac.uk/pdbsum/1c9f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1c9f ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c9f OCA], [https://pdbe.org/1c9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c9f RCSB], [https://www.ebi.ac.uk/pdbsum/1c9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c9f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DFFB_MOUSE DFFB_MOUSE]] Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.  
[https://www.uniprot.org/uniprot/DFFB_MOUSE DFFB_MOUSE] Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/1c9f_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/1c9f_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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</StructureSection>
</StructureSection>
[[Category: Caspases]]
[[Category: Caspases]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Uegaki, K]]
[[Category: Uegaki K]]
[[Category: Yamazaki, T]]
[[Category: Yamazaki T]]
[[Category: Alpha-beta roll]]
[[Category: Hydrolase]]

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