1aud: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 ==U1A-UTRRNA, NMR, 31 STRUCTURES==
-<StructureSection load='1aud' size='340' side='right' caption='[[1aud]], [[NMR_Ensembles_of_Models | 31 NMR models]]' scene=''>
+<StructureSection load='1aud' size='340' side='right'caption='[[1aud]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1aud]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1num 1num]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AUD FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1aud]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1num 1num]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AUD FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">U1A 1-102 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1aud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aud OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1aud RCSB], [http://www.ebi.ac.uk/pdbsum/1aud PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aud OCA], [https://pdbe.org/1aud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aud RCSB], [https://www.ebi.ac.uk/pdbsum/1aud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aud ProSAT]</span></td></tr>
-<table>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/1aud_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/1aud_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
-</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1aud ConSurf].
 <div style="clear:both"></div>
 <div style="background-color:#fffaf0;">
@@ Line 24: / Line 27: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1aud" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Nucleoprotein|Nucleoprotein]]
+*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 == References ==
 <references/>
@@ Line 32: / Line 36: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Allain, F H.T.]]
+[[Category: Large Structures]]
-[[Category: Gubser, C C.]]
+[[Category: Allain FH-T]]
-[[Category: Howe, P W.A.]]
+[[Category: Gubser CC]]
-[[Category: Nagai, K.]]
+[[Category: Howe PWA]]
-[[Category: Neuhaus, D.]]
+[[Category: Nagai K]]
-[[Category: Varani, G.]]
+[[Category: Neuhaus D]]
-[[Category: Rna binding protein-rna complex]]
+[[Category: Varani G]]
-[[Category: Rnp domain]]