2afd: Difference between revisions

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-{{Seed}}
-[[Image:2afd.png|left|200px]]
-<!--
+==Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence==
-The line below this paragraph, containing "STRUCTURE_2afd", creates the "Structure Box" on the page.
+<StructureSection load='2afd' size='340' side='right'caption='[[2afd]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[2afd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AFD FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
--->
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2afd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afd OCA], [https://pdbe.org/2afd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2afd RCSB], [https://www.ebi.ac.uk/pdbsum/2afd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2afd ProSAT], [https://www.topsan.org/Proteins/JCSG/2afd TOPSAN]</span></td></tr>
-{{STRUCTURE_2afd|  PDB=2afd  |  SCENE=  }}
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q8YWG3_NOSS1 Q8YWG3_NOSS1]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afd_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2afd ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Cyanobacteria, such as Anabaena, produce a variety of bioactive natural products via polyketide synthases (PKS), nonribosomal peptide synthetases (NRPS), and hybrid peptide/polyketide pathways. The protein Asl1650, which is a member of the acyl carrier protein family from the cyanobacterium Anabaena sp. PCC 7120, is encoded in a region of the Anabaena genome that is rich in PKS and NRPS genes. To gain new insight into the physiological role of acyl carriers in Anabaena, the solution structure of Asl1650 has been solved by NMR spectroscopy. The protein adopts a twisted antiparallel four-helix bundle fold, with a variant phosphopantetheine-attachment motif positioned at the start of the second helix. Structure comparisons with proteins from other organisms suggest a likely physiological function as a discrete peptidyl carrier protein.
-===Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence===
+Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence.,Johnson MA, Peti W, Herrmann T, Wilson IA, Wuthrich K Protein Sci. 2006 May;15(5):1030-41. Epub 2006 Apr 5. PMID:16597827<ref>PMID:16597827</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_16597827}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 2afd" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 16597827 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_16597827}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-AFD is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFD OCA].
+[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
+[[Category: Herrmann T]]
-==Reference==
+[[Category: Johnson MA]]
-<ref group="xtra">PMID:16597827</ref><references group="xtra"/>
+[[Category: Peti W]]
-[[Category: Anabaena sp.]]
+[[Category: Wilson IA]]
-[[Category: Herrmann, T.]]
+[[Category: Wuthrich K]]
-[[Category: JCSG, Joint Center for Structural Genomics.]]
-[[Category: Johnson, M A.]]
-[[Category: Peti, W.]]
-[[Category: Wilson, I A.]]
-[[Category: Wuthrich, K.]]
-[[Category: Acyl carrier protein family]]
-[[Category: Jcsg]]
-[[Category: Joint center for structural genomic]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: Twisted antiparallel helical bundle]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:06:06 2009''